Results 41 to 50 of about 70,641 (277)

Facility Management using digital Obeya Room by integrating BIM-Lean approaches – an empirical study

Journal of Civil Engineering and Management, 2018
This paper applies a methodology for interdisciplinary Facilities Management (FM) by alingment between Building Information Modeling (BIM) and Lean. Initially, the literature review of BIM, FM and Lean principles.
Daniel Luiz de Mattos Nascimento, Osvaldo Luiz Gonçalves Quelhas, Marcelo Jasmim Meiriño, Rodrigo Goyannes Gusmão Caiado, Simone D. J. Barbosa, Paulo Ivson   +5 more
doaj   +1 more source

Application of the Plan-Do-Check-Act cycle for managing immune-related adverse events [PDF]

, 2022
Abstract BackgroundImmune checkpoint inhibitors (ICIs) sometimes cause immune-related adverse events (irAEs), the timing of occurrence of which is difficult to predict. We created a system to safely manage the patients treated with ICIs who visit hospital during an emergency.MethodsWe utilized the Plan-Do-Check-Act (PDCA) cycle method to ...
Satoshi Hibi, Yuko Shirokawa, Kengo Nanya, Yuko Kato, Nobuto Ito, Takae Kataoka, Takashi Yoshida, Yoshiaki Marumo, Satoshi Kayukawa, Shu Yuasa, Kenji Ina   +10 more
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Управление персоналом с точки зрения менеджмента качества ISO серии 9000 [PDF]

, 2013
Управление персоналом с точки зрения стандартов ISO серии 9000 рассматривается как один из процессов менеджмента ресурсов. Поэтому в основу данного процесса, как и в основу системы менеджмента качества в целом, закладывается цикл «Plan-Do-Check-
Куликовский, Сергей Александрович, Мещерякова, Елена Валентиновна, Тулекбаева, А. К.   +2 more
core  

A3 thinking approach to support knowledge-driven design [PDF]

, 2013
Problem solving is a crucial skill in product development. Any lack of effective decision making at an early design stage will affect productivity and increase costs and the lead time for the other stages of the product development life cycle. This could
Al-Ashaab, Ahmed, Ewers, P., Kassam, A., Maksimovic, Maksim, Mohd Saad, Norhairin, Shehab, Essam, Zhu, L.   +6 more
core   +1 more source

Impact of Pharmacist-Led PDCA Cycle in Reducing Prescription Abandonment: An Action Research from China

Patient Preference and Adherence, 2023
Lisong Lv, Yunfeng Sun, Bo Yang, Chuanwei Xin, Mingwan Zhang Department of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, 310012, People’s Republic of ChinaCorrespondence: Chuanwei Xin, Department of Pharmacy, Tongde Hospital of Zhejiang ...
Lv L, Sun Y, Yang B, Xin C, Zhang M
doaj  

La implementación en el nivel operativo del proceso de enfermería The implementation in the operative level of the nursing process

Revista Latino-Americana de Enfermagem, 1999
El mejoramiento continuo es el marco de referencia utilizado como guía del proceso de enfermería por medio del giro del PDCA. (plan, do, check, act). Traducido en VIDA. (visión, implementación, discernimiento, ajuste).
Nora Agnes Vega Villalobos
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source