Results 111 to 120 of about 9,234,681 (308)
Mirror Lake Management Plan [PDF]
, 2008 Management Plan and Comprehensive Lake Inventory of Mirror Lake in Wolfeboro and Tuftonboro ...
Bottom, Ashley +3 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A SPECIAL CONTROL SYSTEM FOR CONTROLLING THE POSITION OF THE PATH IN THE PLAN
Nauka ta progres transportu, 2008 The special bench mark system for increasing the accuracy of survey of railway track plan is examined.
I. P. Korzhenevych
doaj
Fork in the Road: Alternative Paths to a High Performance U.S. Health System [PDF]
, 2009 Estimates the cost savings and coverage rates of three options for healthcare reform: an insurance exchange with no public plan, a public plan paying Medicare rates, and a public plan paying rates midway between Medicare and private plan ...
Cathy Schoen +3 more
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1
mAbsIn contrast to natural antibodies that rely mainly on the heavy chain to establish contacts with their cognate antigen, we have developed a bispecific antibody format in which the light chain (LC) drives antigen binding and specificity.
Pauline Malinge +13 more
doaj +1 more source
Boy meets goal, boy loses goal, boy gets goal : the nature of feedback between goal-based simulation and understanding systems [PDF]
, 1981 We are designing a goal-based planning and simulation system called REACTOR for a multiple-actor world in which partially formulated plans are monitored during execution, providing feedback to the planner.
Meehan, James R.
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Targeting CEACAM5-positive solid tumors using NILK-2401, a novel CEACAM5xCD47 κλ bispecific antibody
Frontiers in ImmunologyBackgroundBlocking the CD47 “don’t eat me”-signal on tumor cells with monoclonal antibodies or fusion proteins has shown limited clinical activity in hematologic malignancies and solid tumors thus far.
Anja Seckinger +17 more
doaj +1 more source
, 2018 Several European funders announced planS, which suggests that several European nations will ban grantees form publishing in paywalled journals (including hybrid journals that allow one to make an article open access for a fee), and that includes many society journals that are owned by societies but published by large subscription-based publishers. This
openaire +1 more source