Results 111 to 120 of about 9,364,899 (306)
265 CD47xPD-L1 bispecific antibodies for cancer therapy
Journal for ImmunoTherapy of Cancer, 2021 Walter Ferlin +21 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A SPECIAL CONTROL SYSTEM FOR CONTROLLING THE POSITION OF THE PATH IN THE PLAN
Nauka ta progres transportu, 2008 The special bench mark system for increasing the accuracy of survey of railway track plan is examined.
I. P. Korzhenevych
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
, 2015 I was walking on campus today, backpack tight against my shoulders, one headphone in my ear, phone in my back pocket, when I saw a poster calling me a baby killer ...
Anonymous,
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1
mAbsIn contrast to natural antibodies that rely mainly on the heavy chain to establish contacts with their cognate antigen, we have developed a bispecific antibody format in which the light chain (LC) drives antigen binding and specificity.
Pauline Malinge +13 more
doaj +1 more source
, 2018 Several European funders announced planS, which suggests that several European nations will ban grantees form publishing in paywalled journals (including hybrid journals that allow one to make an article open access for a fee), and that includes many society journals that are owned by societies but published by large subscription-based publishers. This
openaire +1 more source
Understanding Health Plan Types: What\u27s in a Name? [PDF]
, 2015 Every year, many employers conduct an open season to let employees select or change their medical plans. Several factors may affect their selection, including choice of care provider and shared cost.
Briscoe, Bonita
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source