Results 151 to 160 of about 3,890,738 (305)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Impact of the expressways

open access: yes
This report, published by the Toledo-Lucas County Plan Commissions in 1961, shows the impact that construction of the I-75 and I-475 expressways will have on Toledo and Lucas County, Ohio.
Toledo (Ohio). Plan Commission
core  

Minutes: Health Plan Task Force: December 16, 1999

open access: yes, 1999
Discussion of Work Plan, Introduction of Buck ConsultantsUniversity of Minnesota: Health Plan Task Force. (1999). Minutes: Health Plan Task Force: December 16, 1999.
University of Minnesota: Health Plan Task Force
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Dynamic Proton arc therapy for paediatric parameningeal rhabdomyosarcoma. [PDF]

open access: yesJ Appl Clin Med Phys
Handeland AH   +6 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Delivery Timing, Out-Of-Pocket Maternity Costs, and Postpartum Care Utilization: An Instrumental Variable Analysis Among Commercially Insured Women. [PDF]

open access: yesHealth Serv Res
Gourevitch RA   +7 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Medicare Advantage Plan Bid Risk Underestimates and Corresponding Insurer Revenues. [PDF]

open access: yesHealth Serv Res
Scheinker D   +4 more
europepmc   +1 more source

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