Results 151 to 160 of about 1,417,198 (268)

The Plan

Canadian Respiratory Journal, 2003
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Relevé en 3D d’une structure souterraine médiévale

Archéopages, 2012
Chhavy-Cyril Tan, Laurent Fournier
doaj   +1 more source

Evaluating the role of plan complexity metrics in online adaptive radiotherapy for pancreatic cancer patients. [PDF]

Med Phys
Cavinato S, Galetto M, Scaggion A, Bettinelli A, Nardini M, Chiloiro G, Romano A, Paiusco M, Boldrini L, Placidi L.   +9 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Version upgrades in treatment planning Systems affect clinical application of a multi-Centre knowledge-based planning model. [PDF]

Tech Innov Patient Support Radiat Oncol
McGoldrick K, Hornby C, Griffin P, Woodford K, Nelli F, Markham C, Kron T, Hardcastle N, Panettieri V.   +8 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A data-driven approach to stock inhaler programming implementation in Chicago Public Schools. [PDF]

Discov Public Health
Patwa M, Cushman J, Lane R, Hardy P, Dhakal S, Zolfo S, Simon J, White J, Green T, Martin MA, Pappalardo AA.   +10 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Racial Disparities and Personal Responsibility Incentives in Medicaid. [PDF]

Health Serv Res
Craig DM, Hernandez EM, Anderson EM, Tran YH, Parker ES, Blackburn J, Gupta S.   +6 more
europepmc   +1 more source