Results 201 to 210 of about 1,417,198 (268)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Ten simple rules for turning your qualifying exam into an NIH-style fellowship proposal: A guide for graduate students. [PDF]

PLoS Comput Biol
Peña-Lima C, Bader CS, Ball BK, Dildine TC, Dissanayake MV, van 't Erve I, Ibrayeva A, Nippert A, Quinn MK, Spinner C, Thompson S, Tomasso A, Botham CM.   +12 more
europepmc   +1 more source

What do health insurance deductibles do to health care spending growth? [PDF]

Int J Health Econ Manag
Lucarelli C, Frean M, Gordon AS, Hua LM, Pauly MV.   +4 more
europepmc   +1 more source

Supporting breast and cervical cancer screening follow-up: qualitative health plan interviews. [PDF]

BMC Health Serv Res
Lin B, Gruschow K, Burke A, Zhou X, Richards TB, Byron SC.   +5 more
europepmc   +1 more source

Daily adaptive radiotherapy in head and neck squamous cell carcinoma can negatively impact organ at risk dosimetry. [PDF]

Clin Transl Radiat Oncol
Enocson H, Haraldsson A, Engström P, Ceberg S, Gebre-Medhin M, Adrian G, Af Rosenschöld PM.   +6 more
europepmc   +1 more source

Notes on Collection and Research, Part 1

Scottish Studies, 1961
H. Henderson B. R. S. Megaw
doaj  

Enrollment in Integrated Special Needs Plans Among Dually Eligible Beneficiaries With Serious Mental Illness.

JAMA Netw Open
McGinty EE, Daumit GL, Zhang M, Zhang Y.
europepmc   +1 more source