Results 241 to 250 of about 9,234,681 (308)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Writing Patient Engagement Effectively Into Grant Applications: Practical Tips for Grant Writers. [PDF]

Health Expect
Hawke LD, Upham K, Seiyad H, Kesteren MRV.   +3 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Daily artificial intelligence-assisted adaptive small margin radiotherapy during trimodal therapy of muscle-invasive bladder cancer. [PDF]

Front Oncol
Blumenfeld P, Levy D, Hillman Y, Feldman J, Fang M, Salhab A, Gofrit ON, Popovtzer A, Wygoda M.   +8 more
europepmc   +1 more source

Margin reduction and optimal prescription isodose model for liver stereotactic radiotherapy with respiratory motion. [PDF]

J Appl Clin Med Phys
Kawahara D, Masuda H, Wada T, Kishi M, Katsuta T, Murakami Y.   +5 more
europepmc   +1 more source

6-Shogaol from Banxia Xiexin Tang: A Potent Regulator of Th17/Treg Balance to Protect Against CPT-11-Induced Intestinal Mucosal Damage. [PDF]

J Microbiol Biotechnol
Wang Y, Pei J, Li C, Zhou J, Zou Y.
europepmc   +1 more source

Prognostic Significance of C-PLAN Index in Patients Treated with Immunotherapy for Non-Small-Cell Lung Cancer. [PDF]

J Clin Med
Nuransoy Cengiz A, Bozkurt O, Cengiz M, Ozkan M, Inanc M, Kefeli U, Cabuk D, Erman M, Kilickap S, Koseci T, Bayir D, Guven DC, Urun M, Cosar R, Sakalar T, Majidova N, Mutlu Ozkan E, Akosman C, Ersoy M, Sahin E, Can Sanci P, Yildiz C, Kolemen E, Agdas G, Kocaaslan E, Turkoğlu E, Yildirim S, Mermit Ercek B, Karakayali A, Arvas H, Kidi MM, Biter S, Yesil Cinkir H, Karahan L, Apaydin Rollas AE.   +34 more
europepmc   +1 more source

Pediatrics Specialty Choice Among Matriculants of MD-Granting US Medical Schools.

JAMA Netw Open
Pineda A, Vinci RJ, Turner A, Andriole D, Grbic D, Nguyen M, Poitevien P.   +6 more
europepmc   +1 more source