Results 131 to 140 of about 1,593,802 (309)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Une gestion globale et solidaire des paysages de la Sèvre Nantaise
La Sèvre Nantaise est un affluent de la rive gauche de la Loire. Au carrefour de l'Anjou, de la Bretagne et du Poitou, les paysages qu'elle anime sont diversifiés tout en étant unis par une dominante bocagère au relief faiblement accentué.
M.A. RANNOU
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Information Outlook, February 1998 [PDF]
Volume 2, Issue 2https://scholarworks.sjsu.edu/sla_io_1998/1001/thumbnail ...
Special Libraries Association
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
El surgimiento de las Escuelas Emergentes de Enfermería en Cuba, significó para la Carrera una formación de nuevo tipo. La masividad e integración del sistema de la Enseñanza Media de la profesión a la Enseñanza Superior, estuvieron entre los rasgos ...
Arturo Alexander Segura Massó +1 more
doaj
Correlated equilibria, incomplete information and coalitional deviations [PDF]
This paper proposes new concepts of strong and coalition-proof correlated equilibria where agents form coalitions at the interim stage and share information about their recommendations in a credible way.
Bloch, Francis, Dutta, Bhaskar
core +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Fin de partie pour les contrats aidés [PDF]
L’été 2017 a été marqué, sur le plan des politiques de l’emploi, par un changement de stratégie majeur du nouveau gouvernement par rapport au précédent quinquennat.
Ducoudre, Bruno
core

