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Planarian Stem Cell Heterogeneity.
Advances in Experimental Medicine and Biology, 2019 Planarian (Platyhelminthes, Triclads) are free-living flatworms endowed with extraordinary regenerative capabilities, i.e., the ability to rebuild any missing body parts also from small fragments. Planarian regenerative capabilities fascinated scientific community since early 1800, including high-standing scientists such as J.T. Morgan and C. M. Child.
S. Alessandra, L. Rossi
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Seminars in Cell & Developmental Biology, 2019
An organizer is defined as a group of cells that secrete specific factors and can change the fate of adjacent cells and instruct a specific pattern. Spemann and Mangold were the first to use the term, when in 1938 they discovered that the dorsal blastopore lip of a salamander embryo induced a secondary axis after transplantation.
Miquel, Sureda-Gomez, Teresa, Adell
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An organizer is defined as a group of cells that secrete specific factors and can change the fate of adjacent cells and instruct a specific pattern. Spemann and Mangold were the first to use the term, when in 1938 they discovered that the dorsal blastopore lip of a salamander embryo induced a secondary axis after transplantation.
Miquel, Sureda-Gomez, Teresa, Adell
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Positional Information and Stem Cells Combine to Result in Planarian Regeneration.
Cold Spring Harbor Perspectives in Biology, 2021The capacity for regeneration is broad in the animal kingdom. Planarians are flatworms that can regenerate any missing body part and their regenerative powers have combined with ease of experimentation to make them a classic regeneration model for more ...
P. Reddien
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Quantification of planarian behaviors
Development, Growth & Differentiation, 2021AbstractResearch on individual behaviors can help to reveal the processes and mechanisms that mediate an animal's habits and interactions with the environment. Importantly, individual behaviors arise as outcomes of genetic programs, morphogenesis, physiological processes, and neural functions; thus, behavioral analyses can be used to detect disorders ...
Takeshi Inoue, Kiyokazu Agata
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Science of the Total Environment, 2021
DAPT (N-[N-(3, 5-difluorophenacetyl)-l-alanyl]-s-phenylglycinet-butyl ester) is a γ-secretase inhibitor that indirectly blocks the activity of Notch pathway.
Zimei Dong +5 more
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DAPT (N-[N-(3, 5-difluorophenacetyl)-l-alanyl]-s-phenylglycinet-butyl ester) is a γ-secretase inhibitor that indirectly blocks the activity of Notch pathway.
Zimei Dong +5 more
semanticscholar +1 more source
Planarian Behaviour and Biochemistry
Nature, 1968Analyses of nucleic acids from planarians removed at various stages of conditioning showed that the RNA/DNA specific activity ratios were significantly different in trained animals during the middle stages of training when learning was not pronounced. The ratios were, however, similar at the terminal stage when the conditioned response performance was ...
W C, Corning, S, Freed
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FUNDAMENTALS OF PLANARIAN REGENERATION
Annual Review of Cell and Developmental Biology, 2004▪ Abstract The principles underlying regeneration in planarians have been explored for over 100 years through surgical manipulations and cellular observations. Planarian regeneration involves the generation of new tissue at the wound site via cell proliferation (blastema formation), and the remodeling of pre-existing tissues to restore symmetry and ...
Peter W, Reddien +1 more
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