Results 41 to 50 of about 1,986,656 (240)

Progressive failure constitutive model of fracture plane in geomaterial based on strain strength distribution

open access: yes, 2013
Progressive failure constitutive model of fracture plane in geomaterial based on strain strength distribution is proposed. The basic assumption is that strain strength of geomaterial comply with a certain distribution law in space.
Li SH(李世海)   +2 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Intermediate strain rate testing methodologies and full-field optical strain measurement techniques for composite materials characterisation

open access: yes, 2014
Two optical full-field strain measurement techniques, Digital Image Correlation and the Grid Method, are applied to characterise the strain-rate dependent constitutive behaviour of composite materials.
Longana, M.L.
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Experimental Study on Deformation and Strength of Silt Under Plane Strain Unloading Conditions

open access: yesApplied Sciences
In geotechnical engineering, operations such as foundation pit excavation, slope cutting, and tunnel boring often involve lateral unloading under plane strain conditions.
Jingchao Jia   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The emergence of high room temperature in-plane and out-of-plane magnetostriction in polycrystalline CoFe2O4 film

open access: yesScientific Reports, 2021
The polycrystalline CoFe2O4 (CFO) film on cantilever substrate of silicon was grown using pulsed laser deposition (PLD) method and investigated its in-plane and out-of-plane magnetostrictive strain at room temperature (300 K) using the indigenous optical
Suman Guchhait, H. Aireddy, A. K. Das
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Plane-strain modeling of smear effects associated with vertical drains

open access: yes, 1997
The present study provides a methodology to include the smear effect of vertical drains in a two-dimensional (2D) plane-strain finite-element model, employing the modified Cam-clay theory.
Buddhima Indraratna (20180526)   +1 more
core   +1 more source

Thermal strain analysis considering in-plane anisotropy for sputtered AlN on c- and a-plane sapphire under high-temperature annealing

open access: yesAIP Advances, 2021
High-temperature annealing of sputtered AlN (Sp-AlN) using a face-to-face configuration is a novel technique that has attracted considerable attention because it can reduce the threading dislocation density of Sp-AlN to 107 cm−2.
Yusuke Hayashi   +5 more
doaj   +1 more source

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