Results 51 to 60 of about 1,986,656 (240)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Increasing the cracking resistance and the survivability of the elements the joints of the sections of the jib crane-manipulating installations of mobile machines [PDF]
Научно-технический вестник Брянского государственного университета, 2015 The new constructive method of increasing the cracking resistance and survivability of eyes swivel boom crane with hydraulic cylinders. Analysis of its efficiency on the basis of predicting the growth of fatigue cracks for the conven-tional and modified ...
Lagerev I.A.
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Civil Engineering Dimension, 2000 This paper presents visual application of a finite element program for plane stress and plane strain problems. The elements used in this program are isoparametric triangular (three nodes) and rectangular (four nodes) and subparametric triangular (six ...
Benjamin Lumantarna
doaj
Petroleum Exploration and Development, 2017 Plane stain assumption is widely used in the simulation of the distribution of stress and displacement around hydraulic fractures. According to the comparison of the solutions of elliptical fracture and plane stain fracture, the applicable conditions of ...
Jinzhou ZHAO +3 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The Formation and Evolution of Shear Bands in Plane Strain Compressed Nickel-Base Superalloy
Metals, 2018 The formation and evolution of shear bands in Inconel 718 nickel-base superalloy under plane strain compression was investigated in the present work.
Bin Tang +5 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Experimentelle Untersuchungen mit Analogmaterial zur Bildung von Falten und Boudins unter konstriktionalen und ebenen Bedingungen [PDF]
, 2006 One possible approach to study systematically the influence of the deformation regime on the geometry of geological structures like folds and boudins is analogue modelling.
Enama Mengong, Mathurin
core
Applied SciencesDue to their superior tribological properties compared to conventional materials, the use of functionally graded materials (FGMs) has long become indispensable in mechanical engineering.
Markus Heß +3 more
doaj +1 more source