Results 61 to 70 of about 1,986,656 (240)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Determining the effect of strain rate on the fracture of sheet steel [PDF]
A key challenge for the automotive industry is to reduce vehicle mass without compromising on crash safety. To achieve this, it is necessary to model local failure in a material rather than design to the overly conservative criteria of total elongation
Beaumont, Richard Adrian
core
Comparative analysis of different finite element models of the soil-buried arch bridge interaction [PDF]
Građevinski Materijali i Konstrukcije, 2019 Comparative analysis is made of different finite element models of a buried arch bridge which is constructed from precast concrete elements. Two static schemes of the bridge structure are considered - a static scheme of rigid connection between all ...
Kazakov Konstantin +2 more
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Characterization of Indentation-Induced Pattern Using Full-Field Strain Measurement
, 2011 [[abstract]]In this study DIC-based strain analysis software was successfully developed and its strain resolution lies on the order of 2.3×10-4-3.1×10-4.
Shih, Ming-Hsiang +3 more
core
Stability charts for unsupported plane strain tunnel headings in homogeneous undrained clay
, 2018 : This paper investigates the stability of plane strain tunnel headings in undrained soils. Using the factor of safety approach via the strength reduction technique, the idealised tunnel heading models are studied using the finite difference program FLAC.
Sams, Mathew +3 more
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source