Results 81 to 90 of about 3,522,268 (236)

Plane stress

open access: yes, 2020
This chapter deals with the static and dynamic analysis of 2D solids, particularly in plane stress. Plane stress analysis refers to problems where the thickness is quite small when compared to other dimensions in the reference plane x–y.
Ferreira A. J. M., Fantuzzi N.
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Numerical modelling of Ti6Al4V(ELI) hierarchical honeycomb structures of order one at the vertices

open access: yesResults in Engineering
Lattice structures are used in engineering industries because of their good mechanical properties, including high stiffness, high strength, as well as specific energy absorption and fracture toughness.
M.I. Chibinyani   +3 more
doaj   +1 more source

A Plane Stress Failure Criterion for Inorganically-Bound Core Materials. [PDF]

open access: yesMaterials (Basel), 2021
Lechner P   +3 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Stress concentration factors of multi-planar tubular XT-joints subjected to out-of-plane bending moments

open access: yes, 2020
The majority of tubular joints commonly found in offshore jacket structures are multi-planar. Investigating the effect of loaded out-of-plane braces on the values of the stress concentration factor (SCF) in offshore tubular joints has been the objective ...
Kouhi, Ahmad   +3 more
core   +1 more source

Study on Shear Slip Characteristics of Sandstone Plane Joints under Normal Dynamic Load Disturbance [PDF]

open access: yesLithosphere
Rock joints are susceptible to slip instability due to dynamic load disturbances such as blasting, earthquakes, and fracturation. A series of direct shear tests under the dynamic load were conducted on sandstone plane joints using the RDS-200xl. The work
Kangyu Wang   +5 more
doaj   +1 more source

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