Results 41 to 50 of about 2,982,700 (318)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Where the fields have no name

Cidades, Comunidades e Território, 2020
This paper discusses the existing urban-rural dichotomy in Portuguese urban planning, assuming its importance on food-provision, a basic human need. Our analysis stems from an historical overview at two scales, regional and municipal, within the Lisbon ...
Teresa Marat-Mendes, João Cunha Borges, Sara Silva Lopes, Mafalda Matos Pereira   +3 more
doaj  

Sustainable Building: High Performance Timber Bridges

Proceedings, 2019
Steel and concrete are fantastic materials that will continue to be fundamental in the future, but we cannot ignore their high energy costs and carbon footprint.
Julio Vivas, Juan Carlos Santos
doaj   +1 more source

Optimization of Cropping Pattern Using Linear Programming Method and Lingo software in Dehgolan Plain in Kurdistan Province, Iran

جغرافیا و پایداری محیط, 2021
The optimal allocation of available production resources to the activities that bring the most benefit to farmers and also minimize water consumption, is one of the most important issues in agriculture management where disregarding this issue leads to ...
Hemen Shariati; Baharak Motamed Vaziri; Masoud Goudarzi; Hasan Ahmadi
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Perspectives of healthcare stakeholders in Nigeria on the impact of COVID-19 on health services

Journal of Public Health in Africa
Background: COVID-19 disrupted critical public health services globally. It is important to understand how the pandemic affected healthcare service delivery and utilisation in Nigeria to guide planning for future public health crises in the country. Aim:
Adeponle O. Adeoye, Yewande T. Nejo, Chinwe L. Ochu, Josephine Bayigga, Rodgers R. Ayebare, Adedayo O. Faneye, Charles O. Adewemimo, Oluwaseun Emmanuel Falayi, Adeniyi Francis Fagbamigbe, Prosper Okonkwo, Adewale Victor Opayele, Gloria Ogochukwu Nwiyi, Sunday Obiajunwa Eziechina, Ikemefule Rex Uzoma, Priscilla Ibekwe, Tamrat Shaweno, Nebiyu Dereje, Francis Kakooza, Mosoka Papa Fallah, Georgina Njideka Odaibo   +19 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Analysis of the Training Model for the Individual Physical Training of Junior Strikers in the Football Game

ACROSS
This research explores the individualised physical training of junior football strikers, emphasising the importance of a well-structured training plan, particularly during the winter season.
Serghei SÎRGHI, Vasile TĂBÎRȚĂ
doaj   +1 more source