Results 61 to 70 of about 8,330,104 (353)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Cooperative Epistemic Multi-Agent Planning for Implicit Coordination [PDF]

, 2017
Epistemic planning can be used for decision making in multi-agent situations with distributed knowledge and capabilities. Recently, Dynamic Epistemic Logic (DEL) has been shown to provide a very natural and expressive framework for epistemic planning. We
Bolander, Thomas, Engesser, Thorsten, Mattmüller, Robert, Nebel, Bernhard   +3 more
core   +2 more sources

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Multi-Agent Planning with Planning Graph [PDF]

, 2003
In this paper, we consider planning for multi-agents situations in STRIPS-like domains with planning graph. Three possible relationships between agents' goals are considered in order to evaluate plans: the agents may be collaborative, adversarial or ...
Bui, The Duy, Jamroga, Wojciech
core   +2 more sources

Monte Carlo Planning method estimates planning horizons during interactive social exchange [PDF]

, 2015
Reciprocating interactions represent a central feature of all human exchanges. They have been the target of various recent experiments, with healthy participants and psychiatric populations engaging as dyads in multi-round exchanges such as a repeated ...
Dayan, P, Hula, A, Montague, PR
core   +1 more source

Contemporary industrial policy and challenges to South America and Brazil [PDF]

Brazilian Journal of Political Economy
We seek to identify the major vectors reconfiguring contemporary industrial policy in the US and the European Union to inform policymaking in South America and Brazil given their specific challenges to economic development.
CARLOS AGUIAR DE MEDEIROS, ESTHER MAJEROWICZ   +1 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Effectiveness of a Theory-Based Educational Intervention on the Constructs of the Health Action Process Approach (HAPA) Model and Sun Protective Behaviors in Male Students [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: The implementation of theory-based interventions is essential for the prevention of skin cancer among male adolescents, given their high levels of sun exposure and low adherence to preventive behaviors.
Qazal Olad Azimi, Isa Mohammadi Zeidi, Hadi Morshedi, Mohammadreza Maleki, Saeed Shahsavari, Amir Pakpoor   +5 more
doaj  

ANALYSIS AND PLANNING OF REGIONAL DEVELOPMENT - CONTEXTUAL VARIABLES TO DEVELOP A MODEL FOR MONITORING FINANCIAL INDICATORS AT REGIONAL LEVEL. [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2013
Application of quantitative techniques in regional analysis can provide an understanding of both the change in time of regional economic performance and the interdependencies between economic sectors, including the use of projections to test the ...
CRIS TINA GRADEA
doaj