Results 51 to 60 of about 2,982,700 (318)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Criteria and practical guidance for determination of brain death in adults (BQCC version)

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
DOI: 10.3969/j.issn.1672-6731.2015.12 ...
Brain Injury Evaluation Quality Control National Health and Family Planning Commission
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Planning beyond Mass Incarceration

, 2020
The policing and penal systems play an oversized role in shaping the built environment and budgets of cities, alongside the lives of urban residents.
Steil, Justin P, Mehta, Aditi, Simpson, Sheryl-Ann   +2 more
core   +1 more source

Simulation of new goods outputting on market in system of enterprise corporate management [PDF]

Marketing i Menedžment Innovacij, 2012
In article agent-based imitating model of outputting of new confectionery product chocolate to market is constructed (chocolate contains special antioxidant successfully counteracting organism ageing).
E.E. Ibragimov
doaj  

Urban Sprawl and Northern European Residential Tourism in the Spanish Mediterranean Coast

Via@, 2016
Residential tourism from Northern European countries has influenced the process of urban development in the Spanish Mediterranean coast. We explain the recent urban growth in Spain (or “Spanish house bubble”) and then show the main characteristics of the
Joan Carles Membrado, Raquel Huete, Alejandro Mantecón   +2 more
doaj   +1 more source

Planning as satisfiability: parallel plans and algorithms for plan search

Artificial Intelligence, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jussi Rintanen, Keijo Heljanko, Ilkka Niemelä   +2 more
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

An Investigation on Construction Project Development Planning Delays in South Africa

Buildings
This article aims to determine the causes of the delays in South African construction project planning, discussing the centralised hierarchical planning system factors, multiple agencies/spheres of government regarding building-permit approval factors ...
Bedan Nyaga Githae, Hakim Hagir, Rebecca Alowo   +2 more
doaj   +1 more source

An evolution of a financial planning in Poland in the years 1945–1990

Prawo Budżetowe Państwa i Samorządu, 2019
Advantages of a multiannual financial planning have been noticed in Poland since the 1960’s. First attempts to provide a long-term financial planning took place in Poland in 1961–1965 (at that time this planning referred to local budgets financial ...
Michał Jędrzejczyk
doaj   +1 more source