Results 81 to 90 of about 14,044 (257)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Polish Consumers’ Perception of Plant-Based Alternatives

, 2023
The study aimed to diagnose to what extent consumers know and consume plant-based alternatives and how they perceive them. The study was carried out on a nationwide sample of adult Poles (N = 1003) between June and September 2023.
Sajdakowska, Marta, Gębski, Jerzy, Jeżewska-Zychowicz, Marzena, Gutkowska, Krystyna, Kosicka-Gębska, Małgorzata   +4 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Multi-Omics and Chemometric Analysis of Aroma Profiles in Plant-Based Milk Alternatives and Cow Milk

Applied Sciences
Rapid expansion of the plant-based milk market has increased the need to understand how the aroma profiles of these alternatives differ from that of dairy milk and how raw material selection and processing influence volatile formation.
Junhan Zhang, Tatsuro Maeda, Shuntaro Isoya, Takayoshi Tanaka, Rin Yoshikawa, Daiki Maehara, Keisuke Motoyanagi, Mari (Maeda) Yamamoto, Kazuya Hasegawa, Tetsuya Araki   +9 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Rising global demand for plant-based milk alternatives - A potential blessing or curse to the NZ dairy industry?

, 2021
This presentation reports a review of existing scholarly and industry literature regarding the current trends in the global plant-based and bovine (mainstream dairy) milk industries.
Metieh, Esther Odiri, Lucock, Xiaomeng
core  

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

A Comparative Analysis of Plant-Based Milk Alternatives Part 1: Composition, Sensory, and Nutritional Value

, 2022
Consumers are becoming increasingly interested in reducing the consumption of animal-based foods for health, sustainability, and ethical reasons.
Pointke, Marcel; 1Division of Quality of Plant Products, Department of Crop Sciences, Faculty of Agriculture, University of Goettingen, 37075 Goettingen, Germany; epawelz@gwdg.de, Albrecht, Elke Herta; 2Division of Ecology of Livestock Production, Department of Animal Sciences, Faculty of Agriculture, University of Goettingen, 37075 Goettingen, Germany; elkeherta.albrecht@uni-goettingen.de (E.H.A.); katrin.geburt@uni-goettingen.de (K.G.); mgerken@gwdg.de (M.G.), Geburt, Katrin, Gerken, Martina; 2Division of Ecology of Livestock Production, Department of Animal Sciences, Faculty of Agriculture, University of Goettingen, 37075 Goettingen, Germany; elkeherta.albrecht@uni-goettingen.de (E.H.A.); katrin.geburt@uni-goettingen.de (K.G.); mgerken@gwdg.de (M.G.), Traulsen, Imke; 3Division Livestock Systems, Department of Animal Sciences, Faculty of Agriculture, University of Goettingen, 37075 Goettingen, Germany; imke.traulsen@uni-goettingen.de, Pointke, Marcel, Traulsen, Imke, Pawelzik, Elke; 1Division of Quality of Plant Products, Department of Crop Sciences, Faculty of Agriculture, University of Goettingen, 37075 Goettingen, Germany; epawelz@gwdg.de, Gerken, Martina, Geburt, Katrin; 2Division of Ecology of Livestock Production, Department of Animal Sciences, Faculty of Agriculture, University of Goettingen, 37075 Goettingen, Germany; elkeherta.albrecht@uni-goettingen.de (E.H.A.); katrin.geburt@uni-goettingen.de (K.G.); mgerken@gwdg.de (M.G.), Pawelzik, Elke, Albrecht, Elke Herta   +11 more
core   +1 more source