Results 111 to 120 of about 4,153,518 (252)

Effect of copper and cultivation condition on the transport, metabolism, and potential risk of tolfenpyrad in pea seedlings (Pisum sativum Linn.)

iScience
Summary: Pesticides and heavy metals are two major classes of environmental pollutants, and their environmental fate requires careful assessment.
Wenhao Xiong, Qin Tang, Yayong Xia, Sanfei Du, Jing Shi, Kankan Zhang   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Plant biology education: A competency‐based vision for the future

Plants, People, Planet
Societal Impact Statement Plant biology is an essential discipline for addressing global challenges from food security to climate change. In order to achieve this, we need to educate plant biologists who can contribute to research, enterprise, policy ...
Katharine Hubbard
doaj   +1 more source

Selenium nanoparticles from Dermacoccus abyssi MT1.1ᵀ improve water status, biomass, and antioxidant defense in tomato under salt stress

iScience
Summary: Salt stress severely limits plant growth and agricultural productivity. Nanoparticles have emerged as a promising strategy to alleviate salinity stress.
Pharada Rangseekaew, Supawitch Hoijang, Sirasit Srinuanpan, Mathurin Meethangdee, Sitthisak Intarasit, Wasu Pathom-aree   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Prevalence and environmental abundance of the TSET complex in cosmopolitan algal groups

iScience
Summary: Classical cell biology paradigms are largely established on animal, fungal, and plant models which constitute a small fraction of eukaryotic diversity.
Mathias Penot-Raquin, Mandeep Sivia, Kelly M. Fafoumi, Raegan Larson, Richard G. Dorrell, Joel B. Dacks   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Comprehensive benchmarking of genome editing quantification methods for plant applications

iScience
Summary: Accurately detecting and quantifying CRISPR edits with high sensitivity is crucial for developing new genome editing applications in plants. This is especially important when analyzing heterogeneous populations from transient expression-based ...
Zheng Gong, Yan Zhang, Di Xia, Sohye Yoon, Peter Alexander Crisp, José Ramón Botella   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source