Results 91 to 100 of about 4,153,518 (252)
Exploring Evolution and Biology of Oomycetes: Integrative and Comparative Genomics [PDF]
, 2013 Diseases that destroy livestock and crops have had catastrophic effects on human civilization, causing starvation and economical losses and continue to be a constant threat to global food production.
Sub Theoretical Biology & Bioinformatics +3 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Effects of Clinorotation on the Host Plant, Medicago truncatula, and Its Microbial Symbionts
Frontiers in Astronomy and Space Sciences, 2016 Understanding the outcome of the plant-microbe symbiosis in altered gravity is vital to developing life support systems for long-distance space travel and colonization of other planets.
Ariel J.C. Dauzart +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Plant Single Cell Type Systems Biology [PDF]
, 2016 The phenotype of a plant in response to a stress condition is the reflection of the molecular responses in different cell-types composing the plant. The multicellular complexity represents a challenge when accessing specific responses of each cell or ...
Libault, Marc +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The first intron of ARF7 is required for expression in root tips
iScienceSummary: Auxin regulates plant growth and development through the transcription factors of the AUXIN RESPONSE FACTOR (ARF) gene family. ARF7 is one of five activators that bind DNA and elicit downstream transcriptional responses. In roots, ARF7 regulates
Jingyi Han +5 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Accelerating domestication of perennial plants with genomics
iScienceSummary: Perennial crops are promising candidates for building climate resilient agricultural systems because they can sustain production in challenging environments and their deep roots mitigate soil erosion, nutrient leaching and preserve soil carbon ...
Renan Souza +4 more
doaj +1 more source
The Application of Synthetic Biology to Elucidation of Plant Mono-, Sesqui-, and Diterpenoid Metabolism [PDF]
, 2015 Plants synthesize a huge variety of terpenoid natural products, including photosynthetic pigments, signaling molecules and defensive substances. These are often produced as complex mixtures, presumably shaped by selective pressure over evolutionary ...
Lu, Xuan +3 more
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