Results 81 to 90 of about 546,038 (302)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Genome-wide patterns of large-size presence/absence variants in sorghum
, 2014 The presence/absence variants (PAVs) are a major source of genome structural variation and have profound effects on phenotypic and genomic variation in animals and humans. However, little is understood about PAVs in plant genomes.
Zhang, Li-Min +12 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
membro dell'editorial board del Journal of integrative plant biology (2009-2017)
, 2017 Journal of Integrative Plant Biology (JIPB) is a peer-reviewed monthly journal that reports the latest plant biology discoveries. It was established in 1952 as Acta Botanica Sinica, and is sponsored by the Botanical Society of China and the Institute of ...
SERINO, Giovanna
core
, 2021 Societal Impact Statement: The “Parts Agenda” is an approach to synthetic biology that fragments genetic resources into functional bioparts to help design and build biological devices and systems. Access and benefit-sharing (ABS), and the issue of how to
Michelle Rourke, Rourke, Michelle
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Final report of the GARNet Advisory Committee on Arabidopsis Systems Biology in the UK, June 2006.
, 2006 Biological research using Arabidopsis thaliana is adopting systems approaches in some areas. Arabidopsis researchers must build the capacity for systems analysis, if the UK’s strength in Arabidopsis biology is to be reflected in sub-systems models that ...
?, ?, Millar, Andrew; id_orcid
core
, 2017 In this study, the effects of different irrigation levels with bio-stimulant applications on leaf area, crown diameter, number of crown, leaf number and plant width were investigated in a variety of Kabarla. The trail was implemented as a 4×2 factorial
kapur, burcak
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source