Results 131 to 140 of about 6,445,889 (340)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The iPlant Collaborative: Cyberinfrastructure for Plant Biology [PDF]

, 2011
The iPlant Collaborative (iPlant) is a United States National Science Foundation (NSF) funded project that aims to create an innovative, comprehensive, and foundational cyberinfrastructure in support of plant biology research (PSCIC, 2006).
Akoglu, A., Andrews, G., Ane, C., Boyle, B., Brutnell, T., Cazes, J., Cranston, K., Donoghue, M. J., Dooley, R., Enquist, B. J., Feng, X., Gendler, K., Gessler, D., Goff, S. A, Gonzales, M, Grene, R., Hanlon, M., Helmke, M., Hilgert, U., Hopkins, N., Jordan, C., Kim, S. J., Kleibenstein, D. J., Koesterke, L., Kubach, A., Kvilekval, K., Leebens-Mack, J., Lenards, A., Lent, M., Lowenthal, D., Lowry, S., Lu, Z., Lyons, E., Manjunath, B.S., Matasci, N., McKay, S., McLay, R., Merchant, N., Micklos, D., Mock, S., Muir, A., Myers, C. R., Narro, M., Noutsos, C., O'Meara, B., Pasternak, S., Piel, W. H., Ram, S., Sanderson, M. J., Skidmore, E., Soltis, D., Soltis, P., Spalding, E. P., Stamatakis, A., Stanzione, D., Stapleton, A. E, Stein, L., Tang, C., Tannen, V., Vaughn, M., Vision, T. J., Wang, L., Ware, D., Welch, S. M., White, J. W.   +64 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The Effects of Clinorotation on the Host Plant, Medicago truncatula, and Its Microbial Symbionts

Frontiers in Astronomy and Space Sciences, 2016
Understanding the outcome of the plant-microbe symbiosis in altered gravity is vital to developing life support systems for long-distance space travel and colonization of other planets.
Ariel J.C. Dauzart, Joshua P. Vandenbrink, John Z Kiss   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Mass spectrometry imaging for plant biology: a review

Phytochemistry Reviews, 2015
Mass spectrometry imaging (MSI) is a developing technique to measure the spatio-temporal distribution of many biomolecules in tissues. Over the preceding decade, MSI has been adopted by plant biologists and applied in a broad range of areas, including ...
B. Boughton, Dinaiz Thinagaran, Daniel Sarabia, A. Bacic, U. Roessner   +4 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Thermodynamical journey in plant biology

Frontiers in Plant Science, 2015
Nonequilibrium irreversible thermodynamics constitute a meaningful point of view suitable to explore life with a rich paradigm. This analytical framework can be used to span the gap from molecular processes to plant function and shows great promise to ...
Adelin Barbacci, V. Magnenet, M. Lahaye
semanticscholar   +1 more source

Plant Chemical Biology [PDF]

Plant and Cell Physiology, 2018
Toshinori Kinoshita, Peter McCourt, Tadao Asami, Keiko U Torii   +3 more
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source