Results 91 to 100 of about 3,000,917 (301)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

GMO’s and Gene Flow: A Plant Breeding Perspective* [PDF]

, 2002
Plant breeding is the art and science of plant improvement via genetic modification. What constitutes plant improvement has to be defined relative to the breeder’s objectives or what the grower, processor, or end-user desires.
Kendall R. Lamkey, Lamkey, Kendall
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Economics in plant breeding: A case focusing on doubled haploid technology [PDF]

With increasing choices in technologies, decision makers responsible for allocating resources in plant breeding programs can benefit from using bioeconomic models.
Pluske, Johanna M.
core  

Morphometric and marker-assisted evaluation of melon (Cucumis melo) segregating population

Discover Plants
Melon is a commercially important crop, yet its adaptation and genetic enhancement, particularly in regions like Bangladesh, remain limited by insufficient comprehensive evaluations of the agronomic performance of diverse global germplasm.
Md Jahid Hasan Jone, Md Nure Adil Siddique, Mehnaj Fatema, Nusrat Jahan Nezu, Upama Mondal, Jobadatun Naher, Mohammad Rashed Hossain   +6 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

PRACTICAL CHALLENGES TO ESTIMATING THE BENEFITS OF AGRICULTURAL R&D: THE CASE OF PLANT BREEDING RESEARCH [PDF]

Interest in the economics of plant breeding first emerged during the late 1960s and early 1970s following the well-known green revolutions in wheat and rice.
Heisey, Paul W., Morris, Michael L.
core  

Genetic variability and breeding potential of Flintisa Composite of maize in two levels of technology

, 2019
The purpose this study was to verify the breeding potential of Flintisa Composite for low (LT) and high (HT) technology of cultivation, and the best selection strategy to be adopted.
Costa Andrade, Joao Antonio da, Costa Andrade, Joao Antonio da [UNESP]   +1 more
core   +1 more source

Genetic diversity of barley landraces from Near East, North Africa and Southern Europe in relation to resistance to powdery mildew

Plant Protection Science, 2002
This study was conducted to determine the resistance to powdery mildew in 218 barley landraces collected in Near East (Israel, Lebanon, Syria, Turkey, Iran, Iraq), North Africa (Egypt, Algeria, Morocco) and Southern Europe (Greece, Bulgaria, Yugoslavia ...
J.H. Czembor, H.J. Czembor, M. Mackey
doaj   +1 more source