Results 91 to 100 of about 610,016 (308)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A multilevel exploration of Avena strigosa diversity as a prelude to promote alternative crop

open access: yesBMC Plant Biology, 2019
Background Sand oat (Avena strigosa Schreb.), one of the four cultivated species of the genus Avena, could be considered as another alternative crop. In gene banks 865 germplasm samples of this species have been preserved that have not been thoroughly ...
Wiesław Podyma   +6 more
doaj   +1 more source

Plant breeding for organic farming: current status and problems in Europe [PDF]

open access: yes, 2005
Compendium is a part of Deliverable 4 of 6th FP SSA project “Environmental friendly food production system: requirements for plant breeding and seed production” (ENVIRFOOD) and contains information about current status and problems in EU regarding to ...
Legzdina, Linda, Skrabule, Ilze
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

COBRA: Coordinating Organic Plant Breeding Activities for Diversity [PDF]

open access: yes
Organic plant production is currently challenged by several pressure factors. Along with perennial problems such as weed control, climate change is threatening to affect crop production through increasing weather variability.

core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Should Europe Further Strengthen Intellectual Property for Plant Breeders? An Analysis of Seed Industry Proposals [PDF]

open access: yes
This paper illustrates the potential negative effects of increasing the scope of plant breeders' rights (PBR) protection, as has been proposed for Europe by leading plant breeding firms. Such a policy could increase the costs for varietal development for
Eaton, Derek J.F.   +1 more
core   +1 more source

Proceedings of the COST SUSVAR/ECO-PB Workshop on organic plant breeding strategies and the use of molecular markers [PDF]

open access: yes, 2005
In many countries,national projects are in progress to investigate the sustainable low-input approach.In the present COST network,these projects are coordinated by means of exchange of materials,establishing common methods for assessment and statistical ...

core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Participatory Plant Breeding for Organic Farming in France, the cauliflower experience at the PAIS [PDF]

open access: yes, 2005
The availability of organic seeds is a great problem for organic farmers. The private sector of plant breeding meets difficulties to answer to the organic farming (OF) demand, characterized by small quantities and a great diversity of criteria and by ...
Chable, Dr Véronique   +1 more
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