Results 101 to 110 of about 243,276 (308)

QTL analysis – did it deliver the goods?

, 2002
QTL analysis was first discussed in 1993 Australian Plant Breeding Conference and since then it has been widely used to develop genetic models for the control of complex traits.
Chalmers, K., Collins, H., Roumeliotis, S., Jefferies, S., Logue, S., Coventry, S., Barr, A., Langridge, P., Eglinton, J.   +8 more
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Comprehensive in-silico analysis of rice B3 transcription factors reveals regulatory and evolutionary insights

Academia Molecular Biology and Genomics
The B3 transcription factors (TFs), which are unique to plants, are crucial for regulating various physiological functions and metabolic pathways, significantly influencing vegetative growth and reproductive processes in plants.
Md. Redwan Ahmed, Jannatul Islam Jyoti, Mehnaj Fatema, Muhammad Mahmudul Hasan, Mohammad Rashed Hossain   +4 more
doaj   +1 more source

A theoretical and practical analysis of the optimum breeding system for perennial ryegrass

, 2011
peer-reviewedThe goal of plant breeding is to effectively and efficiently select for the best phenotypes leading to the development of improved cultivars. The objectives for this review are to describe and critically evaluate breeding methods appropriate
Conaghan, Patrick, Casler, M.D.
core  

In silico development and validation of EST derived new SSR markers for drought tolerance in Cicer arietinum L.

, 2014
Microsatellites have become a marker of choice in plant genetics and breeding research due to their unilocus, multiallelic and highly reproducible nature. In present study EST sequences isolated from chickpea root under water stress were assessed for the
Bhardwaj, Juhi, Kumar, Rajendra, Choi, Insoo, Yadav, Renu S., Kumari, Nilima, Ford, Rebecca, Rajendra, Kumar, Yadav, Renu   +7 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Genotype imputation from low-coverage WGS using haplotype reference panels in cultivated strawberry

BMC Genomics
Background To implement high-throughput sequencing-based genotyping in a strawberry (Fragaria × ananassa) breeding program, we aimed to construct a haplotype reference panel and explore its utility through genotype dosage imputation of low-coverage (1 ...
Tim Koorevaar, Johan H. Willemsen, Richard G. F. Visser, Paul Arens, Chris Maliepaard   +4 more
doaj   +1 more source

Developing high oleic acid in Guizotia abyssinica (L.f.) Cass. by plant breeding

, 2009
P>Oleic acid content was increased from approximately 5-11% to 80-86% in Guizotia abyssinica (L. f.) Cass. materials from Ethiopia after repeated selection and breeding.
Sveriges lantbruksuniversitet., Carlsson, Anders,, Stymne, Sten,, Merker, Arnulf,, Petros, Yohannes,, Fält, Ann-Sofie,   +5 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source