Results 121 to 130 of about 610,016 (308)
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
International Journal of AgronomyChromium (Cr) contamination is a significant threat to sustainable agriculture worldwide. Among different approaches to inhibit Cr contamination in soil, recently fungi have demonstrated their ability to combat the challenges of heavy metal-contaminated ...
Nagarajan Bharathy +6 more
doaj +1 more source
Biotechnology and Plant Breeding
Biotechnology & Biotechnological Equipment, 1993 ABSTRACTPlant breeding is an integrative discipline that is defined by the product, i. e., a crop cultivar. Principles of breeding provide the framework, while technologies (including biotechnology) provide the tools for implementation. The successful execution of plant breeding depends on: availability of genetically variable populations, effective ...
openaire +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Organic seed propagation: current status and problems in Europe [PDF]
, 2005 Report is part of Deliverable 4 of 6th FP SSA project “Environmental friendly food production system: requirements for plant breeding and seed production” (ENVIRFOOD) and contains information about current status and problems in EU regarding to organic ...
Gaile, Zinta
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
BMC Plant BiologyBackground Septoria tritici blotch (STB) is considered to be one of the most destructive foliar wheat diseases and is caused by Zymoseptoria tritici. The yield losses are severe and in Northwestern Europe can reach up to 50%.
Magdalena Radecka-Janusik +5 more
doaj +1 more source
Imagining, making and marketing [PDF]
Working for an organisation that needs to fund its breeding from plant royalties presents some stiff challenges.
Hop, M.E.C.M.
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source