Results 201 to 210 of about 525,389 (295)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity. [PDF]

Front Bioeng Biotechnol
Babu R, Veeramani M, Aadinath W, Muthuvijayan V, Singh S, Srivastava S.   +5 more
europepmc   +1 more source

Knock, knock, who is there? Two studies provide new insights into the translocation of pathogen effectors into plant cells. [PDF]

Plant Cell, 2023
Schuster M.
europepmc   +1 more source

The mobility of enzymes, especially diastases, to penetrate the membranes of plant cells [PDF]

, 1938

openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

From Plants to Plants: Plant-Derived Biological Polymers as Sustainable and Safe Nanocarriers for Direct Delivery of DNA to Plant Cells. [PDF]

Nano Lett
Vinzant K, Rashid M, Clouse DE, Ghosh P, Quadir M, Davis VA, Khodakovskaya MV.   +6 more
europepmc   +1 more source

HISTONE DEACETYLASE 9 transduces heat signal in plant cells. [PDF]

Proc Natl Acad Sci U S A, 2022
Niu Y, Bai J, Liu X, Zhang H, Bao J, Zhao W, Hou Y, Deng X, Yang C, Guo L, Geng Z, Xie H, Wu H, Shen M, Lou X, Tang W, Liu X, Sun D, Cao X, Zheng S.   +19 more
europepmc   +1 more source

Photic excitation and phototropism in single plant cells [PDF]

, 1937

openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Evaluation of Biologics ACE2/Ang(1-7) Encapsulated in Plant Cells for FDA Approval: Safety and Toxicology Studies. [PDF]

Pharmaceutics
Daniell H, Wakade G, Nair SK, Singh R, Emanuel SA, Brock B, Margulies KB.   +6 more
europepmc   +1 more source