A bacterial acetyltransferase targets the protein kinase ZIP1, a positive regulator of plant immunity [PDF]
Pseudomonas syringae is a model bacterial pathogen that penetrates the leaf to reach the plant apoplast, where it replicates causing disease. In order to do that, the pathogen must interfere and suppress a two-tiered plant defense response: PTI (PAMP ...
Beuzon-Lopez, Carmen del Rosario +4 more
core
Analyzing plant defenses in nature [PDF]
A broad range of chemical plant defenses against herbivores has been studied extensively under laboratory conditions. In many of these cases there is still little understanding of their relevance in nature. In natural systems, functional analyses of plant traits are often complicated by an extreme variability, which affects the interaction with higher ...
Daniel J, Ballhorn +3 more
openaire +2 more sources
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Advances in the Involvement of Metals and Metalloids in Plant Defense Response to External Stress
Plants, as sessile organisms, uptake nutrients from the soil. Throughout their whole life cycle, they confront various external biotic and abiotic threats, encompassing harmful element toxicity, pathogen infection, and herbivore attack, posing risks to ...
Lingxiao Zhang +4 more
doaj +1 more source
Carrageenans from red seaweeds as promoters of growth and elicitors of defense response in plants
Plants incessantly encounter abiotic and biotic stresses that limit their growth and productivity. However, conversely, plant growth can also be induced by treatments with various abiotic and biotic elicitors.
Pushp Sheel Shukla +3 more
doaj +1 more source
Effects of virus infection on release of volatile organic compounds from insect-damaged bean, Phaseolus vulgaris [PDF]
Insects can serve as important vectors of plant pathogens, especially viruses. Insect feeding on plants causes the systemic release of a wide range of plant volatile compounds that can serve as an indirect plant defense by attracting natural enemies of ...
Drumwright, B. Alison +4 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Defensive Traits in Young Pine Trees Cluster into Two Divergent Syndromes Related to Early Growth Rate. [PDF]
The combination of defensive traits leads to the evolution of 'plant defense syndromes' which should provide better protection against herbivores than individual traits on their own.
Xoaquín Moreira +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Silicon (Si) is a widely recognized element in plant defense, often enhancing resistance to herbivory by strengthening cell walls and deterring feeding by external herbivores.
Guilherme Ramos Demetrio +3 more
doaj +1 more source

