Results 181 to 190 of about 12,864,433 (337)
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Advancing the automation of plant nucleic acid extraction for rapid diagnosis of plant diseases in space. [PDF]
Front Plant Sci, 2023 Haveman NJ +6 more
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Polarimetric observables for the enhanced visualization of plant diseases. [PDF]
Sci Rep, 2022 Rodríguez C +6 more
europepmc +1 more source
ST-CFI: Swin Transformer with convolutional feature interactions for identifying plant diseases. [PDF]
Sci RepYu S, Xie L, Dai L.
europepmc +1 more source
Editorial: Emergence and re-emergence of plant diseases caused by Xanthomonas species. [PDF]
Front Microbiol, 2022 Coutinho TA, Jacques MA, Jones J.
europepmc +1 more source
Summary of plant diseases in the United States in 1918. IV, Diseases of cereal and forage crops
, 1919 Royal J. Haskell
openalex +2 more sources
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source