Results 71 to 80 of about 442,874 (256)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Convolutional Neural Network for Automatic Identification of Plant Diseases with Limited Data
, 2020 Automated identification of plant diseases is very important for crop protection. Most automated approaches aim to build classification models based on leaf or fruit images.
Ahmed Afifi +2 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2020 Botrytis cinerea is one of the most critical agro-economic phytopathogens and has been reported to cause gray mold disease in more than 1000 plant species.
Md Tabibul Islam +3 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Phytoplasmas and plant diseases: a transkingdom relationship
, 2023 Phytoplasmas or ‘Candidatus Phytoplasma’ are bacteria without cell wall living only in the insect hemolymph and in the plant sieve tubes. After more than 20 years from their discovery their role as plant pathogens is still not resolved for lack of Koch ...
Bertaccini A
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The intracellular inclusions of some plant virus diseases
, 1939 Summary The contents of healthy cells and those infected with a number of different, plant viruses are described. Some of these viruses apparently do not cause the production of intracellular inclusions; others cause the production of amorphous bodies ...
Sheffield, F. M. L., Bawden, F. C.
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Status of induced resistance in plant bacterial host-parasite interactions
, 2005 Induced resistance as a new phenomenon in the biological control against bacterial plant diseases is presented as a review on the last 15 years' research on this aspect.
Zeller, Wolfgang
core