Results 91 to 100 of about 1,276,626 (288)

A mycorrhizae-like gene regulates stem cell and gametophore development in mosses

Nature Communications, 2020
Plant evolution is intimately associated with fungal partners. Here the authors provide evidence that Physcomitrella patens MACRO2, a gene likely derived from early mycorrhizae-like fungi, was transferred to early land plants and plays an important role ...
Shuanghua Wang, Yanlong Guan, Qia Wang, Jinjie Zhao, Guiling Sun, Xiangyang Hu, Mark P. Running, Hang Sun, Jinling Huang   +8 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Measuring Plant Genetic Diversity Using Inter-Simple Sequence Repeats (ISSRS) [PDF]

, 2007
Simple sequence repeats (SSRs) have great utility as they are conserved and present in all eukaryotic genomes. Here we report the use of a simple PCR with fluorescently-labelled primers to amplify inter-SSR markers (ISSRs) for diversity assessments.
Iannetta, Pietro
core  

Natural history of Arabidopsis thaliana and oomycete symbioses [PDF]

, 2008
Molecular ecology of plant–microbe interactions has immediate significance for filling a gap in knowledge between the laboratory discipline of molecular biology and the largely theoretical discipline of evolutionary ecology.
A. Falk, A. H. Ellingboe, A. H. Ellingboe, A. J. Slusarenko, A. P. Rehmany, A. P. Rehmany, A. Riethmüller, A. Roetschi, Arabidopsis Genome Initiative, B. F. Holt, B. M. Tyler, C. Azevedo, C. D. Preston, C. Damgaard, D. Jirage, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. B. Holub, E. G. Bakker, E. Gäumann, E. Koch, E. O. Wilson, E. Speulman, Eric B. Holub, G. Lindau, H. Jönsson, H. Takahashi, H. Voglmayr, H.-M. Chou, J. E. Parker, J. E. Parker, J. Glazebrook, J. Glazebrook, J. M. McDowell, J. M. McDowell, J. N. Thompson, J. N. Thompson, J. N. Thompson, J. O. Borevitz, J. Silvertown, J. Song, J. Staal, J. Win, K. A. Shen, K. Century, K. Kazan, K. Lawton, K. S. Century, K. S. Thompson, L. E. Rose, M. A. Botella, M. A. Botella, M. B. Cooley, M. Damme Van, M. G. M. Aarts, M. Göker, M. H. Borhan, M. H. Borhan, M. J. Austin, M. Tör, N. Aarts, N. Gunn, O. Constantinescu, P. Ayers, P. D. Bittner-Eddy, P. Prusinkiewicz, P. R. Muskett, P. Tornero, Q. H. Shen, R. F. Warren, R. F. Warren, R. Gomulkiewicz, R. L. Allen, R. M. Clark, S. Kamoun, S. McCouch, S. R. Grant, S. Segal, T. Eulgem, T. Eulgem, T. Mitchell-Olds, W. Gassmann, X. Tang   +87 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Human Capital Spillovers in the Workplace: Labor Diversity and Productivity [PDF]

The paper studies the relationship between human capital spillovers and productivity using a unique longitudinal matched employer–employee dataset of Israeli manufacturing plants that contains individual records on all plant employees.
Navon, Guy
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Spiders as surrogate species in ecological monitoring, habitat classification and reserve selection : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Ecology at Massey University, Palmerston North, New Zealand [PDF]

, 2001
The use of invertebrates in the monitoring of terrestrial ecosystems was investigated using spiders as a focal group. In a review of previous literature, spiders were found to meet the majority of criteria required of suitable ecological indicators ...
Coombe, Gil Michael Ian
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source