TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang +11 more
wiley +1 more source
Revisiting gall anatomy through a functional-trait approach across environmental gradients. [PDF]
Gomes-Silva F, Carneiro RGS.
europepmc +1 more source
CHARACTERISTICS OF THE LEAF EPIDERMIS OF CARAGANAPLANTS ON THE ORDOS PLATEAU AND THEIR ECOLOGICAL ADAPTATIONS [PDF]
YANG Jiu-Yan +4 more
openaire +1 more source
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li +8 more
wiley +1 more source
Characterization of Bioactive Composition and Structural Properties of Epidermis and Cortex Tissues in Edible Cactus [<i>Opuntia ficus-indica</i> (L.) Mill.] Cladodes at Different Maturity Stages. [PDF]
Boontiang K +3 more
europepmc +1 more source
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li +14 more
wiley +1 more source
Structures and physiological functions of silica bodies in the epidermis of rice plants
We characterized silica structures in the epidermis of rice plant leaves and investigated their physiological functions from optical and mechanical viewpoints. By treating the distribution of silica bodies as a triangular lattice in the xy plane, and performing a theoretical optical analysis on this lattice, we discovered that a reduction in the ...
openaire +1 more source
Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos +17 more
wiley +1 more source
What fresh cell is this? Building a single-cell atlas of developing grass leaves in Brachypodium distachyon. [PDF]
Fattorini R.
europepmc +1 more source

