Results 201 to 210 of about 100,460 (290)

Peeking into pit fields - A new model of secondary plasmodesmata formation [PDF]

open access: yes, 2008
Akman, O.   +4 more
core   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao   +7 more
wiley   +1 more source

Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine

open access: yesAdvanced Science, EarlyView.
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan   +24 more
wiley   +1 more source

Salicylic acid mitigates arsenic-induced toxicity in wheat by enhancing growth and anatomical traits. [PDF]

open access: yesPlant Signal Behav
Ali U   +9 more
europepmc   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

open access: yesAdvanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang   +10 more
wiley   +1 more source

Resilience in aridity: from biomass reduction to antioxidant accumulation in sewan grass. [PDF]

open access: yesBMC Plant Biol
Bibi S   +5 more
europepmc   +1 more source

Structures and physiological functions of silica bodies in the epidermis of rice plants

open access: yesStructures and physiological functions of silica bodies in the epidermis of rice plants
We characterized silica structures in the epidermis of rice plant leaves and investigated their physiological functions from optical and mechanical viewpoints. By treating the distribution of silica bodies as a triangular lattice in the xy plane, and performing a theoretical optical analysis on this lattice, we discovered that a reduction in the ...
openaire  

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

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