Comprehensive insights into the development of arabidopsis trichomes by single-nucleus RNA-seq. [PDF]
Chen H, Shen X, Lu Y.
europepmc +1 more source
Peeking into pit fields - A new model of secondary plasmodesmata formation [PDF]
Akman, O. +4 more
core +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
The impact of genome duplication on agronomically valuable traits in Ribes nigrum L.: a morpho-anatomical, physiological and cytogenetic evaluation. [PDF]
Machlańska A +3 more
europepmc +1 more source
Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan +24 more
wiley +1 more source
Salicylic acid mitigates arsenic-induced toxicity in wheat by enhancing growth and anatomical traits. [PDF]
Ali U +9 more
europepmc +1 more source
Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang +10 more
wiley +1 more source
Resilience in aridity: from biomass reduction to antioxidant accumulation in sewan grass. [PDF]
Bibi S +5 more
europepmc +1 more source
Structures and physiological functions of silica bodies in the epidermis of rice plants
We characterized silica structures in the epidermis of rice plant leaves and investigated their physiological functions from optical and mechanical viewpoints. By treating the distribution of silica bodies as a triangular lattice in the xy plane, and performing a theoretical optical analysis on this lattice, we discovered that a reduction in the ...
openaire
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source

