Results 81 to 90 of about 236,719 (353)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

??????? ?????? ???????? ?? ???? ?????? ?????(Lepidium aucheri boiss) ? ????? ???????? ???????

open access: yesمجلة علوم ذي قار, 2019
         The present study amide to extracts the essential oils from Lepidium aucheri  boiss ,where  it  was   collected  in   March  2015 from   the   northern  of   Nasiriyah  city  and  it   was  classified .
حسام محمد كريدي   +1 more
doaj   +2 more sources

Potential of essential oils in control of pathogenic plant viruses [PDF]

open access: yesActa Agriculturae Serbica
Essential oils are complex mixtures of aromatic compounds produced through secondary metabolism in plants. They contain various substances such as hydrocarbons, alcohols, ketones, aldehydes, organic acids, and phenols.
Golijan-Pantović Jelena   +7 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

In vitro Antifungal Effects of Various Essential Oils against Aspergillus Crown Rot of Peanut

open access: yesTurkish Journal of Agriculture: Food Science and Technology
Synthetic fungicides that combat plant pathogenic fungi can enhance crop yields, ensuring stable crop production and market quality. However, the increase in the use of fungicides may cause to development of fungicide-resistant pathogen strains and the ...
Merve Oğuz, Yusuf Gümüş, Soner Soylu
doaj   +1 more source

Prospective of Essential Oils of the Genus Mentha as Biopesticides: A Review

open access: yesFrontiers in Plant Science, 2018
Mentha is a genus from the family Lamiaceae, whose essential oils has long been used in various forms such as in management of plant pathogens and insect pests, in traditional medicine as well as in culinary and cosmetics.
Pooja Singh, Abhay K. Pandey
doaj   +1 more source

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