Results 91 to 100 of about 9,099,146 (297)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Effectiveness of encapsulated plant growth-promoting bacteria, Acinetobacter sp. and organic supplements on the growth and nutrient contents enhancement in chilli plant [PDF]

Aims: This study was aimed to determine the effectiveness of previously isolated plant growth-promoting bacteria (PGPR) (Acinetobacter sp. SR R-12) and organic supplements on the growth and nutrient content of chilli plant during its vegetative growth ...
Othman, Nur Maizatul, Hajad, Siti Solemah, Ali Tan, Kee Zuan, Saiman, Mohd Faris, Shamsuddin, Aida Soraya, Hamid, Nur’Amira   +5 more
core   +1 more source

Genomic and functional analyses reveal Pseudomonas granadensis CT364 is a plant growth-promoting endophyte

BMC Microbiology
Background Plant-associated endophytes offer promising agricultural, environmental, and biotechnological applications. Despite their potential utility, difficulties in culturing these microorganisms under laboratory conditions have limited both their ...
Eva Cea Torrescassana, Maria del Carmen Montero-Calasanz, Marc Knight, Jem Stach, Thomas P. Howard   +4 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Identification of rice blast disease-suppressing bacterial strains from the rhizosphere of rice grown in Pakistan. [PDF]

, 2009
Sixteen bacterial strains isolated from the roots and rhizosphere of rice plants growing in saline and non-saline soils from the Shorkot area of Pakistan were tested for their ability to promote plant growth and reduce the incidence of rice blast disease.
Price, Adam H., Naureen, Zakira, Hafeez, Fauzia Y., Roberts, Michael R   +3 more
core   +2 more sources

Evaluation of Rhizosphere Bacteria Associated with Spinacia oleracea for Plant Growth-Promoting Potentials in Bida, Niger State, Nigeria

UMYU Journal of Microbiology Research
The study aimed to assess the rhizosphere bacteria of the spinach plant (Spinacia oleracea) for their growth-promoting potentials.  Rhizosphere soil samples were collected from three different farmlands within Bida metropolis, namely Bangaie, Wuya, and ...
Asma’u Muhammad Abdullahi, Abdullahi Dabban Idris, Habiba Muhammad Abdullahi, Mohammed Babadoko Aliyu, Oluwatoyosi Felicia Ajayi   +4 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Potential of Bacillus sp. SNRUSA4 for Plant Growth Promotion and Biological Control Against Bacterial and Fusarium Wilt in Tomato [PDF]

Anais da Academia Brasileira de Ciências
Tomato cultivation worldwide faces problems with bacterial wilt and Fusarium wilt, which cause significant yield losses. This study evaluated Bacillus sp.
SUWAPHA SAWIPHAK, AROON WONGJIRATTHITI
doaj   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source