Results 151 to 160 of about 111,332 (298)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Modulating alfalfa growth: impacts of plant growth regulators on physiology, architecture, and seed yield. [PDF]

BMC Plant Biol
Wang X, Liu Y, Sui X, Li K, Yimingniyazi A, Jin L, Lang M.   +6 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Effects of plant growth regulators on Orobanche coerulescens seed germination. [PDF]

Bot Stud
Wang YH, Lin KH, Tseng YH, Chen CI, Chen CC, Wang CW, Huang MY.   +6 more
europepmc   +1 more source

Mediation of conifer root growth by mycorrhizal fungi and plant growth regulators

Many mycorrhizosphere microorganisms can produce plant growth regulating compounds in vitro. Plant growth regulating compounds are known to mediate root growth and development.
Scagel, Carolyn F.
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Plant Growth Regulators Use in the In Vitro Culture of <i>Agave</i> Species. [PDF]

Plants (Basel)
Sánchez-Mendoza EA, Pérez-Molphe-Balch E, Guzmán-Mendoza R, Ruiz-Aguilar G, García-Munguía AM, Costilla-Salazar R, Núñez-Palenius HG.   +6 more
europepmc   +1 more source

Optimization and reactor-scale production of plant growth regulators by Pleurotus eryngii. [PDF]

3 Biotech, 2023
Doğan B, Yıldız Z, Aksöz N, Eninanç AB, Korkmaz Kahveci BG, Yamaç M.   +5 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Effects of Rootstock and Exogenous Plant Growth Regulators on Volatile Aroma Profiles and Terpenoid-Mediated Defense in Table Grape Fruit. [PDF]

Life (Basel)
Zhao Y, Xu T, Hu L, Guo Y, Chen Z, Wu Y, Yang Z.   +6 more
europepmc   +1 more source