Results 81 to 90 of about 111,332 (298)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Effect of plant growth regulators on fruit growth and quality development of syzygium samarangense (water apple/wax apple) / Adel Mohammed H. Al-Saif [PDF]

open access: yes, 2011
The present study was conducted to investigate the effects of Gibberellic Acid (GA3), Naphthalene Acetic Acid (NAA) and N-2-chloro-4-pyridyl-N-phenylurea (CPPU) on the growth and quality development of water apple/ wax apple (Syzygium samarangense). GA3
Al-Saif, Adel Mohammed H.
core  

Effect of Different Growth Regulators on Plant Growth and Yield of Bottle Gourd (Lagenaria siceraria L.) cv. Arka Bahar

open access: yes, 2022
An experiment was conducted during 2021 to study the effect of different growth regulators on bottle gourd cv. Arka Bahar during kharif season with three growth regulators at different concentrations: Ethrel (100ppm, 200ppm, 300ppm), NAA (150 ppm, 200ppm,
Sabu, Anna   +2 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Effect of Plant Growth Regulators on Growth Parameters of Bottle Gourd (Lagenaria siceraria) cv. MGH-4

open access: yes, 2022
An experiment entitled " Effect of plant growth regulators on growth, yield and fruit quality of Bottle Gourd (Lagenaria siceraria) cv. MGH-4" was conducted at Horticulture Research Field, Department of Horticulture, Naini Agricultural Institute, Sam ...
Gangwar, Vishal   +6 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Transcriptome and Hormone Analysis Revealed Jasmonic Acid-Mediated Immune Responses of Potato (Solanum tuberosum) to Potato Spindle Tuber Viroid Infection

open access: yesAntioxidants
Potato is a globally important non-cereal crop in which infection with potato spindle tuber viroid (PSTVd) can cause stunted growth and significantly reduce tuber yield.
Iva Marković   +9 more
doaj   +1 more source

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