Results 111 to 120 of about 42,080 (302)

Onion RBS for Disorders Diagnosis and Treatment [PDF]

, 2016
: This research included the design of an initial expert system which helps farmers and specialists to diagnose and provide appropriate advice on onion plant diseases; furthermore, the management of knowledge used in the expert system was discussed.
Ali, Alajrami, Randa, Qassas
core  

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source

On the simulation of enzymatic digest patterns: the fragmentation of oligomeric and polymeric galacturonides by endo-polygalacturonase II

, 2006
A simulation methodology for predicting the time-course of enzymatic digestions is described. The model is based solely on the enzyme's subsite architecture and concomitant binding energies.
Allen, André-Leroux, Armand, Benen, Bonnin, Bussink, Cameron, Cameron, Cameron, Daas, Daas, Daas, Daas, Davies, Dea, DeVries, Goodall, Goubet, Grant Reid, Gyöngyi, Henrissat, Henrissat, Henrissat, Jonathan J. Hunt, King, Körner, Limberg, Limberg, Martin A.K. Williams, Matsumoto, McCleary, Nitta, Ostgaard, Pagès, Pagès, Randall Cameron, Rexová-Benková, Ridley, Ström, Suganuma, Thoma, Thoma, Van Santen, Williams, Williams, Williams   +45 more
core   +1 more source

Uses of Polymeric Nanoparticles Derived from Plant Gum

Proceedings International, 2020
Nanocarriers can be used to carry different types of materials, for instance, drugs, and play a major role in therapy. In this study, gum was collected and subjected to water extract, used for various bioactive studies. It was purified and characterized.
openaire   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang, Yuan Fang, Lingli Jin, Dongyang Liu, Yicheng Liu, Ruijia Zheng, Liyun Yong, Xin Wu, Longliang Qiao, Meiyan Wang, Fengfeng Cai   +10 more
wiley   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Characterization of edible films made with plant carbohydrates for food packaging: A comprehensive review

Carbohydrate Polymer Technologies and Applications
Edible films (EFs) based on plant polysaccharides (e.g., pectin, starch, cellulose, plant gums) offer sustainable alternatives to synthetic food packaging, enhancing mechanical strength, antimicrobial and antioxidant properties, and extending food shelf ...
Zahra Esfandiari, Bahram Hassani, Iraj Karimi Sani, Anis Talebi, Farzad Mohammadi, Shahin Zomorodi, Mohammad Kaveh, Elham Assadpour, Seyedeh Mahsa Khodaei, Hadi Eghbaljoo, Hassan Gholizadeh, Mahmood Alizadeh Sani, Seid Mahdi Jafari   +12 more
doaj   +1 more source

Hepatocyte BPGM Induces RET Lactylation and Macrophage Reprogramming to Promote Tumorigenesis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Mechanistic schematic diagram.BPGM promotes the expression level of RET by increasing the lactylation of RET‐K549 and inhibiting its ubiquitination levels in HCC cells. Furthermore, BPGM in HCC cells could also promote M2 polarization in macrophages through lactate secretion. Both of the mechanisms could promote the progression of HCC. ABSTRACT Aerobic
Jiajia Zhang, Lu Shi, Liangliang Lin, Yang Zhang, Miao Zhang, Lili Wu, Yong Xia, Yaqiong Zhang, Peng Han, Likun Zhuang, Liang Shi   +10 more
wiley   +1 more source

Noncariogenic Sweeteners: Sugar Substitutes for Caries Control [PDF]

, 1987
The evidence is clear that the incidence of dental caries is related to the frequency of eating sugar. The use of sugar substitutes is a suggested way of reducing sugar intake.
Abrams, Richard A., Ayers, Curt S.
core   +1 more source