Results 121 to 130 of about 114,229 (306)

An artificial metalloenzyme biosensor can detect ethylene gas in fruits and Arabidopsis leaves

Nature Communications, 2019
Existing methods to detect ethylene in plant tissue typically require gas chromatography or use ethylene-dependent gene expression as a proxy. Here Vong et al.
Kenward Vong, Shohei Eda, Yasuhiro Kadota, Igor Nasibullin, Takanori Wakatake, Satoshi Yokoshima, Ken Shirasu, Katsunori Tanaka   +7 more
doaj   +1 more source

The Extended Plant Immune System

Molecular Plant-Microbe Interactions®
When disease resistance was still viewed as a vague physiological response rather than a genetically defined process, Harold Henry Flor laid the foundation for our modern understanding of plant immunity with his gene-for-gene concept. Initially developed for simple host–pathogen interactions, this idea has evolved into a more complex framework in which
openaire   +3 more sources

An endogenous danger detection system in "Arabidopsis thaliana": the AtPep peptides and their receptors

, 2014
Plants use a plethora of sophisticated detection systems to recognize a variety of attackers and to subsequently initiate defense responses. A well-known paradigm in this context is the perception of microbe-associated molecular patterns (MAMPs) by ...
Klauser, Dominik Roman
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Non-Specific Lipid Transfer Proteins in Triticum kiharae Dorof. et Migush.: Identification, Characterization and Expression Profiling in Response to Pathogens and Resistance Inducers

Pathogens, 2019
Non-specific lipid-transfer proteins (nsLTPs) represent a family of plant antimicrobial peptides (AMPs) implicated in diverse physiological processes.
Tatyana I. Odintsova, Marina P. Slezina, Ekaterina A. Istomina, Tatyana V. Korostyleva, Alexey S. Kovtun, Artem S. Kasianov, Larisa A. Shcherbakova, Alexander M. Kudryavtsev   +7 more
doaj   +1 more source

Trained immunity and immune priming in plants and invertebrates

eLife
Immune memory has long been thought to be restricted to the adaptive immune system of vertebrates. However, several lines of evidence have changed our understanding of immune memory and have shattered the strict separation between innate and adaptive immunity.
Kurtz, J., Andino, R., Boraschi, D., Contreras-Garduño, J., Kachroo, A., Khan, I., Lanz Mendoza, H., Mukherjee, K., Peuß, R., Ton, J.   +9 more
openaire   +3 more sources

Hormonal signaling in plant immunity

, 2016
Insect hervivores and pathogens are a major problem in agriculture and therefore, control of these pests and diseases is essential. For this, understanding the plant immune response can be instrumental. The plant hormones salicylic acid (SA) and jasmonic
Sub Plant-Microbe Interactions, Plant Microbe Interactions, Caarls, L.   +2 more
core  

ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 Repress SALICYLIC ACID INDUCTION DEFICIENT2 Expression to Negatively Regulate Plant Innate Immunity in Arabidopsis [PDF]

, 2009
Pathogen/microbe-associated molecular patterns (PAMPs/MAMPs) trigger plant immunity that forms the first line inducible defenses in plants. The regulatory mechanism of MAMP-triggered immunity, however, is poorly understood. Here, we show that Arabidopsis
Lin, Huiqiong, Cui, Haitao, Li Xue, Xin Li, Zhou, Jian-Min, Hugo Germain, Jian-Min Zhou, Huamin Chen, Tang, Xiaoyan, Huiqiong Lin, Chintamanani, Satya, Germain, Hugo, Zuo, Jianru, Li, Xin, Guo, Hongwei, Satya Chintamanani, Run Cai, Xue, Li, Jianru Zuo, Xiaoyan Tang, Haitao Cui, Hongwei Guo, Chen, Huamin, Cai, Run   +23 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source