Results 51 to 60 of about 289,938 (307)

Conserved effector families render Phytophthora species vulnerable to recognition by NLR receptors in nonhost plants

Nature Communications
NLR receptor is suggested as a component of plant nonhost resistance (NHR). However, the evolutionary process of how plants develop receptors for recognizing broad-spectrum pathogens is still elusive. Here, we observe that multiple RxLR effector families
Soohyun Oh, Myung-Shin Kim, Hui Jeong Kang, Taewon Kim, Junhyeong Kong, Doil Choi   +5 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

An Arabidopsis nonhost resistance gene, IMPORTIN ALPHA 2 provides immunity against rice sheath blight pathogen, Rhizoctonia solani

Current Research in Microbial Sciences, 2022
There is neither resistant rice cultivar nor any control measure against Rhizoctonia solani AG-1 IA (RS), causal of sheath blight and a major threat to global rice production. Rice is a host and Arabidopsis is a nonhost with underlying nonhost resistance
Daraksha Parween, Binod Bihari Sahu
doaj   +1 more source

Viruses mobilize plant immunity to deter nonvector insect herbivores. [PDF]

, 2019
A parasite-infected host may promote performance of associated insect vectors; but possible parasite effects on nonvector insects have been largely unexplored. Here, we show that Begomovirus, the largest genus of plant viruses and transmitted exclusively
Cai, Congxi, Du, Jie, Fang, Rong-Xiang, Kliebenstein, Daniel J, Li, Ran, Liu, Shu-Sheng, Sun, Yanwei, Wang, Mengyu, Wang, Qiaomei, Yao, Xiangmei, Ye, Jian, Zhao, Pingzhi, Zou, Zhen   +12 more
core   +1 more source

Comparative analysis of plant immune receptor architectures uncovers host proteins likely targeted by pathogens. [PDF]

, 2016
BACKGROUND: Plants deploy immune receptors to detect pathogen-derived molecules and initiate defense responses. Intracellular plant immune receptors called nucleotide-binding leucine-rich repeat (NLR) proteins contain a central nucleotide-binding (NB ...
Cevik, Volkan, Dagdas, Gulay, Jones, Jonathan, Krasileva, Ksenia, Sarris, Panagiotis   +4 more
core   +11 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

A plant NLR receptor employs ABA central regulator PP2C-SnRK2 to activate antiviral immunity

Nature Communications
Defence against pathogens relies on intracellular nucleotide-binding, leucine-rich repeat immune receptors (NLRs) in plants. Hormone signaling including abscisic acid (ABA) pathways are activated by NLRs and play pivotal roles in defence against ...
Shen Huang, Chunli Wang, Zixuan Ding, Yaqian Zhao, Jing Dai, Jia Li, Haining Huang, Tongkai Wang, Min Zhu, Mingfeng Feng, Yinghua Ji, Zhongkai Zhang, Xiaorong Tao   +12 more
doaj   +1 more source

Conserved Subgroups of the Plant-Specific RWP-RK Transcription Factor Family Are Present in Oomycete Pathogens

Frontiers in Microbiology, 2020
Nitrogen is a major constituent of proteins, chlorophyll, nucleotides, and hormones and has profound effects on plant growth and productivity. RWP-RK family transcription factors (TFs) are key regulators that bind to cis-acting elements in the promoter ...
Maozhu Yin, Maozhu Yin, Maozhu Yin, Zhichao Zhang, Zhichao Zhang, Zhichao Zhang, Mingrun Xuan, Mingrun Xuan, Mingrun Xuan, Hui Feng, Hui Feng, Hui Feng, Wenwu Ye, Wenwu Ye, Wenwu Ye, Xiaobo Zheng, Xiaobo Zheng, Xiaobo Zheng, Yuanchao Wang, Yuanchao Wang, Yuanchao Wang   +20 more
doaj   +1 more source

Comprehensive analysis of the membrane phosphoproteome regulated by oligogalacturonides in Arabidopsis thaliana [PDF]

, 2016
Early changes in the Arabidopsis thaliana membrane phosphoproteome in response to oligogalacturonides (OGs), a class of plant damage-associated molecular patterns (DAMPs), were analyzed by two complementary proteomic approaches.
DE LORENZO, Giulia, MATTEI, Maria Benedetta, PONTIGGIA, Daniela, SPINELLI, FRANCESCO   +3 more
core   +1 more source

Pathogen manipulation of chloroplast function triggers a light-dependent immune recognition [PDF]

, 2020
In plants and animals, nucleotide-binding leucine-rich repeat (NLR) proteins are intracellular immune sensors that recognize and eliminate a wide range of invading pathogens.
Bozkurt, Tolga O., Dong, Suomeng, Duggan, Cian, Gao, Chuyun, Huang, Jie, Kamoun, Sophien, Savage, Zachary, Sun, Biying, Vleeshouwers, Vivianne G. A. A., Wang, Yuanchao, Wu, Chih-Hang, Xu, Huawei, Yan, Tingxiu, Zhang, Fan   +13 more
core   +1 more source