An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Microscopic features of raw materials of Laurus nobilis L.
Aim. The urgent task of contemporary pharmacy is the continuation of studies of popular medicinal plants’ raw materials, for example, laurel, for further adjustment of its application.
S. G. Musienko, V. S. Kislichenko
doaj +1 more source
Gene expression changes in phosphorus deficient potato (Solanum tuberosum L.) leaves and the potential for diagnostic gene expression markers [PDF]
Background: There are compelling economic and environmental reasons to reduce our reliance on inorganic phosphate (Pi) fertilisers. Better management of Pi fertiliser applications is one option to improve the efficiency of Pi fertiliser use, whilst ...
John P. Hammond +24 more
core +2 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Characterization of polyphenols in leaves of four desiccation tolerant plant families [PDF]
Includes bibliographical references.Polyphenols in plants are known to act as antioxidants, antimicrobials, antifungal, photoreceptors, visual attractors and as light screens.
Dzobo, Kevin
core +1 more source
Preliminary estimates of mass-loss rates, changes in stable isotope composition, and invertebrate colonisation of evergreen and deciduous leaves in a Waikato, New Zealand, stream. [PDF]
Rates of mass loss are important in the choice of tree species used in riparian rehabilitation because leaves that break down fast should contribute to stream food-webs more rapidly than leaves that break down more slowly.
Laboyrie, J. Lee +3 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A PRELIMINARY STUDY OF LEAD DEPOSITION ON PLANT LEAVES IN TEHRAN [PDF]
Fifty-nine samples of washed and unwashed leaves of 4 species of plants in Tehran and 24 similar samples of the suburb (as control) were analyzed for Pb content.
H.Farsam +1 more
doaj +1 more source
On Compass Plants and Twisting of Leaves [PDF]
n ...
openaire +2 more sources

