Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Sources of the Deposition of Submicron Soot Particles on Plant Leaves. [PDF]
Liu Q.
europepmc +1 more source
Attachment Performance of Stick Insects (Phasmatodea) on Plant Leaves with Different Surface Characteristics. [PDF]
Burack J, Gorb SN, Büscher TH.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Construction costs and tradeoffs in carnivorous pitcher plant leaves: towards a pitcher leaf economics spectrum. [PDF]
Gilbert KJ +12 more
europepmc +1 more source
Green synthesis of multi-functional carbon dots from medicinal plant leaves for antimicrobial, antioxidant, and bioimaging applications. [PDF]
Gedda G +5 more
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Multiclass semantic segmentation for prime disease detection with severity level identification in Citrus plant leaves. [PDF]
Dinesh P, Lakshmanan R.
europepmc +1 more source

