Visual Molecular Dynamics Investigations of the Impact of Hydrophobic Nanoparticles on Prognosis of Alzheimer’s Disease and Cancers [PDF]
, 2012 The possible impact of hydrophobic lectin nanoparticles on the prognosis and progression of Alzheimer's disease (AD) and cancers was investigated by Visual Molecular Dynamics (VMD) computer modeling programs available from the Beckmann Advanced ...
I. C. Baianu, M Charles, V. I. Prisecaru
core +1 more source
Advanced Science, EarlyView.Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibiting sialylation reduces inflammation and oxidative stress in IVD tissues, suggesting new therapeutic possibilities.
Kieran Joyce +8 more
wiley +1 more source
Lectin Engineering, a Molecular Evolutionary Approach to Expanding the Lectin Utilities
Molecules, 2015 In the post genomic era, glycomics—the systematic study of all glycan structures of a given cell or organism—has emerged as an indispensable technology in various fields of biology and medicine.
Dan Hu, Hiroaki Tateno, Jun Hirabayashi
doaj +1 more source
In silico Comparative Analysis of Gene and Protein of Plant Lectins [PDF]
, 2023 Fathiya Khairiya +5 more
openalex +1 more source
Competitiveness and communication for effective inoculation byRhizobium, Bradyrhizobium and vesicular-arbuscular mycorrhiza fungi [PDF]
, 1994 After a short summary on the ecology and rhizosphere biology of symbiotic bacteria and vesicular-arbuscular (VA) mycorrhiza fungi and their application as microbial inocula, results on competitiveness and communication are summarized. Stress factors such
A. A. T. Vargas +55 more
core +1 more source
Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages
Advanced Science, EarlyView.Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu +14 more
wiley +1 more source
Overview of Genus Prosopis Toxicity Reports and its Beneficial Biomedical Properties [PDF]
, 2016 Secondary plant metabolites are regarded as promising sources of plant-protecting substances and they are one of the most important lines of plant defense against pests. The range of cellular targets for these substances is very wide and covers metabolic
Gamarra Luques, Carlos Diego +3 more
core +1 more source
Nanoscale Mapping of the Subcellular Glycosylation Landscape
Advanced Science, EarlyView.Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter +4 more
wiley +1 more source
Network Analysis Reveals the Recognition Mechanism for Dimer Formation of Bulb-type Lectins
Scientific Reports, 2017 The bulb-type lectins are proteins consist of three sequential beta-sheet subdomains that bind to specific carbohydrates to perform certain biological functions.
Yunjie Zhao +9 more
doaj +1 more source
Lactic acid bacteria isolated from poultry protect the intestinal epithelial cells of chickens from in vitro wheat germ agglutinin-induced cytotoxicity [PDF]
, 2018 Poultry fed on wheat-based diets regularly ingest wheat germ agglutinin (WGA) that has toxic effects in vitro on intestinal epithelial cells (IEC) obtained from 14-d-old broilers.
Apella, Maria Cristina +4 more
core +1 more source