Results 121 to 130 of about 30,002 (291)
Gut-brain axis: Review on the association between Parkinson's disease and plant lectins. [PDF]
Arch Clin Cases, 2022 Moin K +6 more
europepmc +1 more source
Advanced Science, EarlyView.AAA ABSTRACT Protein glycosylation and phosphorylation are critical post‐translational modifications (PTMs) governing nearly all cellular functions, yet their analysis remains challenging due to reliance on costly and unsustainable enrichment materials.
Jiaying Li +9 more
wiley +1 more source
Multivalent Glycopolymer Design Unlocks Antimicrobial Activity of 2‐Deoxyglucose
Angewandte Chemie, EarlyView.New approaches to combat antimicrobial‐resistant pathogens are needed. Here, scaffolding a nonmetabolizable sugar (2DG) on a polymer backbone is shown to significantly improve its antimicrobial activity. ABSTRACT With the increasing prevalence of multidrug‐resistant (MDR) pathogens, last‐line therapeutics such as cyclic peptides are insufficient ...
Sungjin Jeon +4 more
wiley +2 more sources
The future of plant lectinology: Advanced technologies and computational tools
BBA AdvancesLectins play crucial roles in many biological processes and serve as tools in fields ranging from agriculture to biomedicine. While classical methods for lectin discovery and characterization were foundational for the field, they often lack sensitivity ...
Vinicius J.S. Osterne +3 more
doaj +1 more source
Plant lectins as potent Anti-coronaviruses, Anti-inflammatory, antinociceptive and antiulcer agents. [PDF]
Saudi J Biol Sci, 2022 Konozy E, Osman M, Dirar A.
europepmc +1 more source
Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Advanced Science, EarlyView.Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka +9 more
wiley +1 more source
Ribosome-Inactivating Proteins from Plants: A Historical Overview
Molecules, 2016 This review provides a historical overview of the research on plant ribosome-inactivating proteins (RIPs), starting from the first studies at the end of eighteenth century involving the purification of abrin and ricin, as well as the immunological ...
Andrea Bolognesi +4 more
doaj +1 more source
Plant lectins as prospective antiviral biomolecules in the search for COVID-19 eradication strategies. [PDF]
Biomed Pharmacother, 2022 Ahmed MN +4 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
Advanced Science, EarlyView.This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao +6 more
wiley +1 more source