Results 71 to 80 of about 18,810 (305)

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica   +6 more
wiley   +1 more source

Enceladus Farm: Can plants grow with Enceladus' water? (Preliminary Report) [PDF]

open access: yesarXiv, 2020
Enceladus is a saturnian satellite that should have liquid water inside of it (subsurface ocean). Measurements and experiments on water plume from Enceladus have revealed that Enceladus' ocean contains several salts such as NaCl. On the Earth, salt in soil has become a serious problem for agriculture, and importance of salt-tolerant plants are ...
arxiv  

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim   +9 more
wiley   +1 more source

Confirmation that T cell receptor activation is digital, not analog. Hence individual T cell cytolytic capacity is independent of initial stimulation strength [PDF]

open access: yesarXiv, 2018
Whether a sub-optimum lymphocyte stimulus is achieved by lowering ligand concentration, or decreasing its affinity, initial TCR activation responses are likely to be digital. We now know for cultured peripheral blood mononuclear cells (PBMCs), when activated by plant lectins such as concanavalin-A (Con-A), that the responding cells are T cells, and ...
arxiv  

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo   +11 more
wiley   +1 more source

Targeting and Recognition of Toll-Like Receptors by Plant and Pathogen Lectins

open access: yesFrontiers in Immunology, 2017
We have reported that some lectins act as agonists of toll-like receptors (TLRs) and have immunomodulatory properties. The plant lectin ArtinM, for example, interacts with N-glycans of TLR2, whereas other lectins of microbial origin interact with TLR2 ...
Rafael Ricci-Azevedo   +2 more
doaj   +1 more source

Eurythmic Dancing with Plants -- Measuring Plant Response to Human Body Movement in an Anthroposophic Environment [PDF]

open access: yesarXiv, 2020
This paper describes three experiments measuring interaction of humans with garden plants. In particular, body movement of a human conducting eurythmic dances near the plants (beetroots, tomatoes, lettuce) is correlated with the action potential measured by a plant SpikerBox, a device measuring the electrical activity of plants, and the leaf movement ...
arxiv  

Machine‐Learning‐Aided Advanced Electrochemical Biosensors

open access: yesAdvanced Materials, EarlyView.
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan   +9 more
wiley   +1 more source

An automated reading of semi-quantitative hemagglutination results in microplates: Micro-assay for plant lectins

open access: yesOpen Chemistry, 2023
An automated, qualitative and semi-quantitative micro-assay for the detection of plant lectins also known as phyto-agglutinins (glycoproteins; have exciting applications in medicines) is described as an alternative to conventional assays.
Gulzar Haseena   +9 more
doaj   +1 more source

A Highly Adaptable Hydrogen Bond Re‐Orientation (HyBRO) Strategy for Multiscale Vasculature Fabrication

open access: yesAdvanced Materials, EarlyView.
A novel hydrogen bond re‐orientation (HyBRO) strategy enables three‐dimensional (3D) printing of vascular microchannel networks with high accuracy. By switching sacrificial material interactions with nonsolvents, HyBRO prevents swelling and deformation, enabling accurate hierarchical channels spanning a tenfold size range.
Zhencheng Liao   +5 more
wiley   +1 more source

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