Results 91 to 100 of about 12,355 (250)
Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
The future of plant lectinology: Advanced technologies and computational tools
Lectins play crucial roles in many biological processes and serve as tools in fields ranging from agriculture to biomedicine. While classical methods for lectin discovery and characterization were foundational for the field, they often lack sensitivity ...
Vinicius J.S. Osterne +3 more
doaj +1 more source
Plants have evolved a sophisticated immune system that allows them to recognize invading pathogens by specialized receptors. Carbohydrate-binding proteins or lectins are part of this immune system and especially the lectins that reside in the ...
Sofie Van Holle +2 more
doaj +1 more source
Next Generation Hosts for Protein Recognition, Assembly and More
The original design of synthetic receptors for proteins was based on macrocycles with a hydrophobic core and a polar/charged periphery. This design, geared towards protein recognition, facilitates receptor self‐assembly. Macrocycle oligomerization, in turn, contributes to protein assembly as evidenced in many cocrystal structures.
Peter B. Crowley
wiley +1 more source
Precision Chemistry for Protein Lysine Modification
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
A series of hydrosoluble BODIPY pH probes allows building biomimetic pH sensors based on micrometric oil‐in‐water droplets. The ratiometric fluorescence output offers quantitative information on the evolution of pH during phagosome maturation. ABSTRACT We present a modular biomimetic fluorescent sensing platform designed to precisely interrogate the ...
Sophie Michelis +5 more
wiley +1 more source
Oogenesis and germinal bed morphology of the brown anole (A. sagrei)
Abstract Background The brown anole is a model species of the genus Anolis, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in ...
Bonnie K. Kircher +12 more
wiley +1 more source
Plant Cell Protolytic Enzymes Activity under Exposure to Lectins of Endophytic and Epiphytic Azospirillum Strains [PDF]
We studied the ability of lectins isolated from the surface of the two strains of nitrogen-fixing soil bacteria of the genus Azospirillum, A. brasilense Sp7 (epiphytic) and A.
S.A. Alen’kina, V.E. Nikitina
doaj
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely +14 more
wiley +1 more source
Dynamics of Heparin Translocations Through Solid‐State Nanopores
Carbohydrates can be detected with solid‐state nanopores, but their kinetics of voltage‐driven passage are fast. To better understand the dynamics of passage of these biomolecules and the role of electrophoresis and electroosmosis, we studied the translocation characteristics of heparin as a function of salt concentration, pH and voltage polarity ...
Kexin Zhao +5 more
wiley +1 more source

