Results 61 to 70 of about 507 (180)

Prospects of mushroom molecular pharming R&D and market potential [PDF]

open access: yes, 2012
菇菌產業在世界各國均屬高產值精緻農業,也是少數市場需求能以3-10 %年複合成長率穩定增加的經濟作物。目前在全球的銷售值約達280-300億美元,其生產潛力和市場價值均不容忽視。分子農場在一般係指以植物生產具有醫藥或商業價值之產物的技術平台。菇菌類分子農場是建立在植物分子農場的既有優勢,利用食用菇種富含蛋白質(佔菇體乾重19-35%)、具有微生物生長快速、比植物更接近動物的蛋白質轉譯後修飾作用,且栽培環境條件易於控制等等諸多優勢,成為發展分子農場的最佳平台。就菇菌產業而言,分子農場無論在品種改良 ...
呂映慈, Lyu Y.T.
core  

Structure and function of plant toxins (with emphasis on cystine knot toxins) [PDF]

open access: yes, 2002
Plant toxins are substances produced and secreted by plants to defend themselves against predators. In a broad sense, this includes all substances that have a toxic effect on targeted organisms, whether they are microbes, other plants, insects, or higher
Sando, L.   +4 more
core   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

open access: yesAnimal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu   +8 more
wiley   +1 more source

HLA‐B*15:21 carrier status is a susceptibility factor of carbamazepine‐induced nonimmediate cutaneous adverse reactions in HLA‐B*15:02‐negative patients: A retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
After HLA‐B*15:02 screening, the residual risk of carbamazepine‐induced nonimmediate cutaneous adverse reactions is 0.059. Among these HLA‐B*15:02‐negative cases, HLA‐B*15:11 and HLA‐B*15:21 carrier status significantly increases the risk of carbamazepine‐induced nonimmediate cADR.
Warit Ruanglertboon   +11 more
wiley   +1 more source

Shape‐directed formation of T8/T6 Zn–siloxane clusters and their deep‐UV shielding properties

open access: yesBulletin of the Korean Chemical Society, EarlyView.
The shape and conformational characteristics of silane substituents direct the assembly of Zn–siloxane clusters into conventional T8 or rare T6 siloxane frameworks. Non‐planar cyclic substituents selectively promote T6 formation through steric effects, while the resulting clusters exhibit deep‐ultraviolet absorption and can be processed into ...
Dopil Kim   +5 more
wiley   +1 more source

Polyphenol oxidase silencing avoids protein crosslinking and enzymatic browning in Nicotiana benthamiana leaf extracts [PDF]

open access: yes
Oxidation in extracts from agroinfiltrated leaves leads to browning and protein precipitation. Here we show that silencing of polyphenol oxidase (PPO) in Nicotiana benthamiana suppresses enzymatic browning and avoids crosslinking of endogenous proteins ...
Mahadevan C   +4 more
europepmc   +3 more sources

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

open access: yesBMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu   +8 more
wiley   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor   +12 more
wiley   +1 more source

Vaginal host–microbe signatures linked to placental outcomes in mares

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule   +7 more
wiley   +1 more source

From Farming to "Pharming". Risks and Policy Challenges of Third Generation GM Crops [PDF]

open access: yes
Commercial and academic activities in the production of pharmaceuticals or other substances of industrial interests from genetically modified plants, i.e. molecular farming, have so far centred in the USA and Canada. Recent increases in EU activities and
Armin Spörk
core  

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