Results 61 to 70 of about 176,680 (266)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Interlaboratory Validation of High-Throughput Sequencing for the Detection of Viruses and Viroids in Apple, Grapevine, and Stone Fruits

PhytoFrontiers
High-throughput sequencing (HTS) has been demonstrated to be a paradigm shift for post-entry quarantine programs by increasing their ability to detect unknown plant viruses that have remained undetected by conventional diagnostic tools.
Peter Abrahamian, Weili Cai, Schyler O. Nunziata, Kristian Stevens, Xiaojun Hu, Min Sook Hwang, Larissa C. Costa, Charles A. Belanger, Benjamin Atha, Yu Yang, Nourolah Soltani, Oscar P. Hurtado-Gonzales, Maher Al Rwahnih, Yazmín Rivera   +13 more
doaj   +1 more source

The Plant – Pathogen Interactions

Microbiology Indonesia, 2010
Interaction between plants and their pathogens is complex, involving multifaceted recognition of pathogens by the plants and, on the other hand, subtle evasion from the pathogens.
CAHYA PRIHATNA
doaj   +1 more source

Machine learning identifies straightforward early warning rules for human Puumala hantavirus outbreaks

Scientific Reports, 2023
Human Puumala virus (PUUV) infections in Germany fluctuate multi-annually, following fluctuations of the bank vole population size. We applied a transformation to the annual incidence values and established a heuristic method to develop a straightforward
Orestis Kazasidis, Jens Jacob
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Genome-Informed Real-Time Polymerase Chain Reaction for Detection of Erwinia pyrifoliae, the Causal Agent of Asian Pear Blight

PhytoFrontiers
Erwinia pyrifoliae causes blight symptoms on pears (Pyrus spp.), apple (Malus spp.), and strawberry (Fragaria × ananassa), with up to 40% losses in strawberry observed during a 2013 outbreak in the Netherlands.
Jarred Yasuhara-Bell, Vessela Mavrodieva, Yazmín Rivera   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Functional Transcomplementation between Wheat Dwarf Virus Strains in Wheat and Barley

Viruses, 2019
Wheat dwarf virus, transmitted by the leafhopper Psammotettix alienus in a persistent, non-propagative manner, infects numerous species from the Poaceae family. Data associated with wheat dwarf virus (WDV) suggest that some isolates preferentially infect
Isabelle Abt, Marlène Souquet, Gersende Angot, Romain Mabon, Sylvie Dallot, Gaël Thébaud, Emmanuel Jacquot   +6 more
doaj   +1 more source