Developing Emericellopsis sp. XJ1056 as a versatile fungal platform for high-yield biosynthesis of nonribosomal peptides: a case study on beauvericin [PDF]
Frontiers in MicrobiologyIntroductionBeauvericin is a cyclodepsipeptide with insecticidal, antitumor, and antimicrobial activities, yet its application is limited by low yields. Filamentous fungi represent promising cell factories for complex natural products, but constraints in
Yutong Ai +14 more
doaj +2 more sources
Beauvericin and Enniatins: In Vitro Intestinal Effects [PDF]
Toxins, 2020 Food and feed contamination by emerging mycotoxins beauvericin and enniatins is a worldwide health problem and a matter of great concern nowadays, and data on their toxicological behavior are still scarce.
Alessia Bertero +3 more
doaj +4 more sources
Study on In Vitro Metabolism and In Vivo Pharmacokinetics of Beauvericin
Toxins, 2022 Beauvericin (BEA) is a well-known mycotoxin produced by many fungi, including Beaveria bassiana. The purpose of this study was to evaluate the in vitro distribution and metabolism characteristics as well as the in vivo pharmacokinetic (PK) profile of BEA.
Yu Yuan +3 more
doaj +3 more sources
Beauvericin, a Bioactive Compound Produced by Fungi: A Short Review
Molecules, 2012 Beauvericin is a cyclic hexadepsipeptide mycotoxin, which has insecticidal, antimicrobial, antiviral and cytotoxic activities. It is a potential agent for pesticides and medicines.
Lijian Xu, Qinggui Wang, Xu Lijian
exaly +3 more sources
Beauvericin K, a New Antifungal Beauvericin Analogue from a Marine-derived sp [PDF]
Natural Product Communications, 2016 Chemical investigation of a Chinese collection of a marine-derived fungus, Fusarium sp., led to the characterization of beauvericin K, a new analogue of beauvericin.
Xiuli Xu +5 more
doaj +3 more sources
Enniatins and Beauvericin as Emerging Mycotoxins in the Context of Climate Change in Europe [PDF]
ToxinsEmerging mycotoxins are unregulated natural toxins, often detected in small-grain cereal crops. They are produced by various Fusarium molds and have been reported in surveys conducted across Europe.
Francesca De Battistis +5 more
doaj +2 more sources
Cytotoxic Activities and Molecular Mechanisms of the Beauvericin and Beauvericin G1 Microbial Products against Melanoma Cells [PDF]
Molecules, 2020 Melanoma is the most serious type of skin cancer and remains highly drug-resistant. Therefore, the discovery of novel effective agents against melanoma is in high demand.
Haet Nim Lim +5 more
doaj +3 more sources
EFSA JournalThe European Commission (EC) asked EFSA to assess the genotoxicity of beauvericin (BEA). Relevant information, including that which has become available since the 2014 Scientific Opinion on the risks to human and animal health related to the presence of ...
EFSA Panel on Contaminants in the Food Chain (CONTAM) +22 more
doaj +3 more sources
Toxins, 2017 Recently, in vitro anti-cancer properties of beauvericin, a fungal metabolite were shown in various cancer cell lines. In this study, we assessed the specificity of this effect by comparing beauvericin cytotoxicity in malignant versus non-malignant cells.
Petra Heffeter +2 more
exaly +3 more sources
A putative ABC transporter gene, CcT1, is involved in beauvericin synthesis, conidiation, and oxidative stress resistance in Cordyceps chanhua [PDF]
Microbiology SpectrumCordyceps chanhua is a traditional Chinese medicinal fungus renowned for producing a variety of bioactive compounds, including beauvericin (BEA). BEA has garnered significant attention due to its therapeutic potential and associated food safety concerns.
Zhimin Liu +8 more
doaj +2 more sources