Results 151 to 160 of about 7,993,758 (351)

Viral proteins resolve the virus-vector conundrum during hemipteran-mediated transmission by subverting salicylic acid signaling pathway

open access: yesNature Communications
Hemipteran insects transmit viruses when infesting plants, during which vectors activate salicylic acid (SA)-regulated antiviral defenses. How vector-borne plant viruses circumvent these antiviral defenses is largely unexplored.
Jing-Ru Zhang   +8 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Integrated Disease Management, Adaptation and Genomics of Fungal Plant Pathogens in Cropping Systems [PDF]

open access: yes
Crop production systems contribute significantly to maintaining global food security. These systems often involve the cultivation of single cultivars in highly homogenised environments to meet demands.
Hobson, K   +5 more
core   +1 more source

Editorial: Necrotrophic Fungal Plant Pathogens

open access: yesFrontiers in Plant Science, 2022
Antonieta De Cal   +2 more
doaj   +1 more source

A rare, evolutionarily conserved venom protein benefits endoparasitism across parasitoids

open access: yesCell Genomics
Summary: Although many venom proteins and other parasitic effectors have been identified in various specific systems of parasitoids, key elements that contribute to parasitic success across a broad range of taxa remain largely unexplored.
Zhi Dong   +14 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Editorial: Emerging Fungal Plant Pathogens

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Samantha C. Karunarathna   +4 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Functional analysis of all succinate dehydrogenase subunits in Fusarium fujikuroi

open access: yesPhytopathology Research
Fusarium fujikuroi, the causal agent of rice bakanae disease (RBD), contains five succinate dehydrogenase (Sdh) subunits: FfSdhA, FfSdhB, FfSdhC1, FfSdhC2, and FfSdhD.
Mengyuan Fan   +7 more
doaj   +1 more source

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