Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Sexual reproduction in Phytophthora infestans [PDF]
, 2007 Potato late blight, caused by the oomycete Phytophthora infestans, is one of the most devastating plant diseases worldwide. It is becoming increasingly difficult to control the disease in Sweden, leading to an ever more intensified use of fungicides in ...
Andersson, Björn
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
EDIS, 2018 This identification sheet was designed to assist packinghouse employees to identify the early yet subtle symptoms of citrus black spot. Proper identification of citrus black spot prevents the rejection of international fruit shipments.
Megan M. Dewdney +2 more
doaj
Editorial: Antimicrobial peptides and mRNA therapy: Clinical, Veterinary, and plant pathology perspectives with special attention to combatting MDR pathogens. [PDF]
Front Microbiol, 2022 Fodor A, Méhi O, Brivio M.
europepmc +1 more source
Kiwifruit bacterial canker in 'Hayward' kiwifruit : the application of observational study design and epidemiological techniques to the study of disease outbreaks affecting plant health : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Epidemiology, Institute of Veterinary, Animal and Biomedical Sciences at Massey University, Manawatu, New Zealand [PDF]
, 2017 Bacterial canker of kiwifruit, caused by Pseudomonas syringae pv. actinidiae (Psa) biovar 3, was first recorded in New Zealand in November 2010 and quickly made production of the goldfleshed kiwifruit cultivar, ‘Hort16A’, which is highly susceptible to
Froud, Karyn Janine
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Pothos (Epipremnum aureum) Diseases: Identification and Control in Commercial Greenhouse Production
EDIS, 2018 Pothos is a tropical ornamental vine that has been grown commercially in the US for almost 100 years and is used for a variety of aesthetic purposes. This 5-page publication addresses identification and treatment of common diseases encountered during ...
David J. Norman, Gul Shad Ali
doaj
Understanding the ramifications of quantitative ordinal scales on accuracy of estimates of disease severity and data analysis in plant pathology. [PDF]
Trop Plant Pathol, 2022 Chiang KS, Bock CH.
europepmc +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source