Results 111 to 120 of about 6,054,127 (329)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The effect of pre-sowing radiation treatment of seeds on the productivity of Matricaria chamomilla L. plants

Інтродукція Рослин
The study aimed to determine the effect of radiation exposure on the productivity of the above-ground mass of different cultivars of Matricaria сhamomilla L. under the conditions of using fertilizing biological preparations. The cultivars M. chamomilla ‘
Olena Andrushchenko, Jamal Rakhmetov, Oleksandra Kravets, Oksana Sokol, Nadiya Dzhurenko, Olena Palamarchuk, Svitlana Pchelovska, Lyudmila Glushchenko, Mykola Kuchuk   +8 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Studies on quinones and related compounds in higher plants. V. Model experiments for the preparation of tritium-labeled precursors for the biosynthetic studies of prenylnaphthoquinone congeners.

, 1977
Kenichiro Inoue, Yoshinori Shiobara, Hiroyuki Inouye   +2 more
openalex   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Preparation, Properties and Use of Nanocellulose from Non-Wood Plant Materials

, 2020
Valerii Barbash, O. V. Yaschenko
openalex   +1 more source

Persisting effects of seed bed preparation and early grazing on plant communities in grassland restoration [PDF]

, 2023
Aure Durbecq, Renaud Jaunatre, Élise Buisson, Cassandra Favale, Nolwenn Maudieu, Armin Bischoff   +5 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plant Stem Cells in Cosmetic Industry

Plants
It is interesting to note that some of the most lucrative commercial products available today are derived from plant cell cultures. Apple, grape, ginger, rice, and other plant stem cells have been successfully and extensively utilized in cosmetic ...
Vassiliki Gardiki, Panagoula Pavlou, Angeliki Siamidi, Spyridon Papageorgiou, Apostolos Papadopoulos, Kriton Iakovou, Athanasia Varvaresou   +6 more
doaj   +1 more source

Preparation of some protein samples from the fresh leaves of plants and the sulphur distributions of the preparations [PDF]

, 1938
J. W. H. Lugg
openalex   +1 more source