Results 121 to 130 of about 339,881 (366)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
How safe are herbal products? [PDF]
, 2000 In the search for cures for his ailments, man discovered many healing and toxic properties of plants. Some were found to cure certain diseases while others were found to exert dramatic effects on the body.
Forte, John Stephen
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The Great Healing Potential Hidden in Plant Preparations of Antioxidant Properties: A Return to Nature? [PDF]
Oxid Med Cell Longev, 2020 Kiełczykowska M, Musik I.
europepmc +1 more source
Prolongation of AV nodal refractoriness by Ruta graveolens in isolated rat hearts [PDF]
, 2008 Objectives: To evaluate concentration-dependent effects of total extract of Rusta graveolens and its purified alkaloid fraction on the nodal basic and functional properties.
Golalipour, M.J. +4 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
ANALYSIS OF FICUS CARICA L. – VOLATILE COMPONENTS AND MINERAL CONTENT [PDF]
, 2013 Ficus carica L. is a well-known Mediterranean plant, its fructus - the fig- is consumed widely, mostly in the southern region of Europe. It’s a member of the Moraceae family, one of the earliest crops.
Balázs, Andrea +4 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The beneficiation of tailing of coal preparation plant by heavy-medium cyclone [PDF]
, 2018 Ataallah Bahrami +4 more
openalex +1 more source
PREPARATION OF A COMBINATION OF NANO- MEDICINAL PLANTS AS ANTIOXIDANTS AND MICROORGANISMS
, 2023 M. S. Al-Hamdani Hamdia +1 more
openalex +2 more sources